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What Next | Daily News and Analysis

The Lab Leak Theory

What Next | Daily News and Analysis

Slate Podcasts

News, News Commentary, Daily News

4.32.4K Ratings

🗓️ 13 April 2021

⏱️ 27 minutes

🧾️ Download transcript

Summary

How one theory about COVID-19’s origins went from the fringes to the mainstream -- and why it just might be plausible. Guest: Alina Chan, postdoctoral fellow at the Broad Institute of MIT and Harvard. Slate Plus members get bonus segments and ad-free podcast feeds. Sign up now. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

A year ago, most people were cooped up trying to keep themselves occupied by making sourdough

0:10.8

starter or binging Netflix.

0:14.0

Alina Chan, she was trying to keep busy too.

0:17.2

Only Alina is a genetic engineer.

0:19.9

So scientists when they see something strange happening, they want to study it.

0:23.0

It's just like an inherent characteristic of scientists is that you want to solve problems.

0:28.8

And last year, the strange thing that was happening was COVID, which meant Alina was asking herself,

0:34.4

What could I do at home?

0:38.7

This is how Alina began doing some of the most controversial research into the coronavirus.

0:44.2

From her home, the same way a lot of us have been working.

0:47.6

It all started with the virus's genetic blueprint.

0:50.6

And so at that time, the news came out that this virus was genetically stable.

0:55.9

It was changing very little. So it looked so stable that at the time, a lot of experts said that

1:02.8

maybe we don't have to worry about our vaccines and our antibodies because the target is so stable.

1:12.0

And it sounds like great news. But it got Alina's attention because she knows a little something

1:16.8

about viral evolution. She'd studied SARS-1, which spread to humans back in 2003.

1:23.2

That virus, it's so closely related to this coronavirus that some people call COVID, SARS-2.

1:31.2

If you look, especially at SARS-1, which is again the most related virus to SARS-2 in terms of

1:38.0

human outbreaks, when you compare SARS-1 to SARS-2, it is striking that there isn't this period of

1:45.1

rapid mutation, adaptation to the host that you could see in SARS-1, but not SARS-2.

1:49.8

So with SARS-1, you could just see it like changing day to day, trying to figure out how to

1:58.3

stick around its host. Not day to day, but between patients. Based on the sequences that they got

...

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