4.6 • 7.3K Ratings
🗓️ 7 October 2025
⏱️ 68 minutes
🧾️ Download transcript
Most people think about heart disease and metabolism when they talk about longevity, but too few talk about joint health. In this episode, you’ll discover how to biohack your joints to prevent pain, reverse damage, and move like you’re decades younger. Host Dave Asprey reveals how functional movement, core stability, and recovery can transform joint health, helping you maintain pain-free performance for life.
Watch this episode on YouTube for the full video experience:
https://www.youtube.com/@DaveAspreyBPR
Dr. Jason Snibbe is a globally recognized, board-certified orthopedic surgeon and a pioneer in advanced, minimally invasive, and robotic surgeries of the shoulder, elbow, hip, and knee. Fellowship-trained in Sports Medicine and Robotic Joint Reconstruction, he has achieved the lowest complication rate at Cedars-Sinai Medical Center and is the official orthopedic surgeon for the Los Angeles Clippers. He also serves as an orthopedic consultant for the Los Angeles Lakers, Los Angeles Sparks, Los Angeles Angels of Anaheim, and Los Angeles Kings. As a founding and managing partner in DOCS Spine and Orthopedics and Docs Surgical Hospital, Dr. Snibbe lectures and trains surgeons around the world in his specialized techniques.
Host Dave Asprey and Dr. Snibbe uncover how weak glutes, poor core engagement, and bad footwear accelerate joint aging, and how functional movement training and fascia care can protect your body from surgery. You’ll learn why proper biomechanics are central to human performance and longevity, how hypermobility and fascia impact neuroplasticity, and the latest biohacking tools for recovery and joint regeneration.
You’ll Learn:
• The real cause of joint damage and how to prevent it
• How to build a stronger core and glutes for long-term joint stability
• Why footwear choices can make or break your movement quality
• The truth about fascia, stretching, and strength training
• When to use PRP, stem cells, and biologics for healing
• How hypermobility affects your joints, brain, and longevity
• Daily mobility and recovery habits that prevent future surgery
They explore how biologics like PRP, stem cells, and exosomes are changing orthopedic recovery and joint repair, and why functional medicine is moving beyond surgery toward regeneration. You’ll hear how precision movement, fascia work, and strength training protect your joints and enhance human performance and longevity.
This is essential listening for anyone serious about biohacking, hacking human performance, improving mobility, and extending longevity. You’ll also learn how neuroplasticity, metabolism, and brain optimization all connect to the way you move.
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: Joint biohacking, Orthopedic regeneration, Functional movement patterns, Core stability training, Glute activation exercises, Fascia mobility, Hypermobility syndrome, Ehlers-Danlos collagen disorder, Foot biomechanics, Pronation and supination, Arch support orthotics, Barefoot gait training, Stem cell joint repair, PRP knee therapy, Exosome orthopedic recovery, Meniscus tear alternatives, Robotic joint surgery, Posture correction, Gait analysis technology, Pain-free longevity
Thank you to our sponsors!
Resources:
• Learn more about Dr. Snibbe’s work: https://www.drjasonsnibbe.com/
• Danger Coffee: https://dangercoffee.com/discount/dave15
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Upgrade Collective: https://www.ourupgradecollective.com
• Upgrade Labs: https://upgradelabs.com
• 40 Years of Zen: https://40yearsofzen.com
Timestamps:
• 0:00 — Trailer
• 1:28 — Introduction
• 2:38 — The Kinetic Chain
• 9:34 — Core and Glutes
• 12:18 — Stretching and Fascia
• 17:32 — Sleep and Recovery
• 18:49 — Vibration Therapy
• 23:47 — Gait and Compensation
• 30:47 — Robotic Surgery
• 34:28 — Future of Medicine
• 39:23 — Footwear Mistakes
• 48:48 — Wearables and Tech
• 55:13 — Stem Cells and Biologics
• 1:01:20 — Final Takeaways
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| 0:00.0 | The number of people between 30 and 60 that are ending up with joint replacement is astronomical. |
| 0:05.9 | The curse we have as a person is we're sleeping every night. |
| 0:08.7 | Every night we're falling asleep and we're still for however long you sleep, |
| 0:12.2 | five hours, eight hours, seven hours, your body's still. |
| 0:15.0 | So you wake up in the morning and your body is stuck. |
| 0:18.0 | It is so critical to stretch your body, work on your flexibility. |
| 0:22.3 | Dr. Jason Snibby is a leading orthopedic surgeon and sports medicine innovator. He's pushing |
| 0:27.3 | the limits of joint care and helping elite athletes recover faster and stronger than ever. His |
| 0:32.1 | innovative approach is redefining how we heal, recover, and get back in the game. |
| 0:36.7 | I had a total knee replacement done by Dr. Jason Snibby, an absolute artist. |
| 0:43.2 | I mean, the best of the best. |
| 0:45.1 | I can't tell you how many patients I've done a hip replacement on who have had foot and ankle |
| 0:50.2 | injuries where they say, you know what? |
| 0:52.2 | I was walking down the street. |
| 0:53.6 | I sprayed my ankle. And then I was limping for a while. |
| 0:56.4 | I was in a boot for three months. |
| 0:58.0 | And then all of a sudden my hip went out. |
| 0:59.9 | What are the top three most important exercises for core stability that are going to stop them from needing a joint surgery later? |
| 1:07.5 | You're listening to The Human Upgrade with Dave Asprey. |
| 1:14.6 | Okay. You're listening to The Human Upgrade with Dave Asprey. If you're a founder or product creator in the biohacking and longevity space, listen up. |
| 1:19.5 | Our industry will hit $100 billion in the next four years. |
| 1:24.0 | Innovation is accelerating and someone is going to own your market. The question is, |
... |
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