The Challenging Realities Of Regime Change In Iran

The Fox News Rundown

FOX News Podcasts

News, Daily News, Politics

3.4 • 1.7K Ratings

🗓️ 2 March 2026

⏱️ 32 minutes

🔗️ Recording | iTunes | RSS

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Summary

The Middle East faces a major geopolitical shift following a joint U.S. and Israeli operation in Iran that resulted in the death of Supreme Leader Ayatollah Ali Khamenei and several top commanders. President Trump ordered the strike with the goal of "giving the country back to the Iranian people," sparking debate in Washington over executive authority and the War Powers Act. Texas Republican Congressman Pat Fallon, a member of the Armed Services and Intelligence Committees, joins the Rundown to discuss the strategic implications of the attack, and the risk of retaliation at home. With 30 million Americans living with a rare disease, is the traditional "blockbuster" drug model failing the approximately one in 11 people who need specialized care? Judy Stecker, founder of Wheeler’s Warriors and former HHS official, joins us to discuss a historic shift at the FDA. From the groundbreaking use of genome editing to treat metabolic diseases to the emotional journey of her son Wheeler, Stecker explains how she believes the science of "genetic patches" has finally outpaced our regulatory system. Plus, commentary by Senior Fellow at the Lexington Institute, Dr. Rebecca Grant. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Transcript

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0:00.0	I'm Ben Dominic. I'm Madison Allworth. I'm Stuart Varney, and this is the Fox News Rundown.
0:08.5	Monday, March 2nd, 2026. I'm Grinnell Scott. The U.S. and Israel struck Iran over the weekend in an
0:16.4	attack that killed Iran's supreme leader. While there is debate on whether President Trump had the authority to act,
0:23.7	many say attacking a state sponsor of terror was the right move.
0:27.9	How do you take an action?
0:30.0	How do you give the president the latitude to take an action without letting your adversary know,
0:34.9	hey, here we come.
0:36.4	I'm Jessica Rosenthal.
0:38.2	A new proposal from the FDA meant to make it easier to treat rare diseases could quicken
0:43.3	the pace toward individualized medicine.
0:45.5	We don't have the regulatory path to appropriately guardrail those new innovations.
0:53.2	So instead, a medicine or a therapy for one has to go through
0:57.6	the same process at a medicine for 300,000. And I'm Dr. Rebecca Grant. I've got the final word on the
1:06.3	Fox Newsundown.
1:13.7	The last week was busy.
1:19.0	In the midst of a continued department of Homeland Security shutdown, President Trump delivered his State of the Union address and the Clintons offered closed door testimony on
1:23.9	what connections they had to disgraced financier Jeffrey Epstein.
1:28.3	But in the early hours of Saturday, President Trump's announcement of an attack on Iran became the top story.
1:35.7	Our objective is to defend the American people by eliminating imminent threats from the Iranian regime.
1:49.1	A vicious group of very hard, terrible people.
1:55.2	The assault resulted in the killing of Iran's supreme leader Ayatollah Khamenei and the loss of some of their top commanders. But Iran's foreign minister, Abbas Arachi, went on ABCs this week to say they're still able to
2:02.4	respond to the attack against them.
	...

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