This episode is brought to you by Rupa Health, Paleovalley, and ButcherBox. Our food supply is dramatically less nutrient rich than it has ever been, and it’s taking a toll on our health. A shocking 99 percent of Americans are nutrient deficient, including over 90 percent who are deficient in omega 3 fats and 50 percent who are deficient in magnesium.  In this episode of my Masterclass series, I am interviewed by my good friend and podcast host, Dhru Purohit, about the top supplements for longevity, especially NAD, which inhibits inflammation, increases metabolism, and increases insulin sensitivity. We also discuss how to critically evaluate supplement research and much more. Dhru Purohit is a podcast host, serial entrepreneur, and investor in the health and wellness industry. His podcast, The Dhru Purohit Podcast, is a top 50 global health podcast with over 30 million unique downloads. His interviews focus on the inner workings of the brain and the body and feature the brightest minds in wellness, medicine, and mindset. This episode is brought to you by Rupa Health, Paleovalley, and ButcherBox.   Rupa Health is a place where Functional Medicine practitioners can access more than 2,000 specialty lab tests from over 20 labs like DUTCH, Vibrant America, Genova, and Great Plains. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com.   Paleovalley is offering my listeners 15% off their entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal.   For a limited time, new subscribers to ButcherBox will receive ground beef FOR LIFE. When you sign up today, ButcherBox will send you 2 lbs of 100% grass-fed, grass-finished beef free in every box for the life of your subscription + $10 off. To receive this offer, go to ButcherBox.com/farmacy.   In this episode, we discuss (audio version / Apple Subscriber version): The value of including supplements in your health routine (4:49 / 1:36)  Top three supplements I recommend (7:03 / 3:43) How to critically review supplement research (26:28 / 21:16) Conventional medicine’s approach to supplements (27:09 / 22:14)  The best supplements for longevity (27:09 / 24:38)  The value of resveratrol (42:38 / 37:22)  Questions from our community on brain health supplement recommendations, how to measure success of supplements, and more (49:32 / 43:55)  Mentioned in this episode: Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin  Long-latency deficiency disease: insights from calcium and vitamin D by Robert P. Heaney