The #1 Fat That’s Silently Destroying Your Metabolism - AI Podcast

Dr. Joseph Mercola - Take Control of Your Health

Briana Mercola

Health & Fitness, Health, Alternative Health

4.6 • 1.5K Ratings

🗓️ 21 July 2025

⏱️ 8 minutes

🔗️ Recording | iTunes | RSS

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Summary

Story at-a-glance

Linoleic acid (LA), a fat found in vegetable oils, accumulates in your tissues and disrupts mitochondrial function, which drains your energy and slows your metabolism
This fat becomes toxic when oxidized, producing harmful byproducts that damage DNA, enzymes, and the machinery your cells need to generate energy
Excess LA damages your gut by interfering with colon cell metabolism, harming beneficial microbes, and promoting inflammation linked to insulin resistance and obesity
LA’s half-life in body fat is about two years, meaning the damage builds up slowly and requires long-term dietary changes to reverse
Cutting out vegetable oils, eating gut-repairing whole foods, and switching to stable fats like grass fed butter and tallow are key steps to restoring your metabolic health

Transcript

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0:00.0	Are you eating a fat that can stay in your tissues for years? Lowering your energy, stressing your
0:05.5	gut, and pushing you toward insulin resistance? Welcome to Dr. Mercola's cellular wisdom. Stay
0:11.5	informed with quick, easy-to-listen summaries of our latest articles, perfect for when you're
0:16.0	on the go. No reading required. Subscribe for free at Mercola.com for the latest health insights.
0:22.2	Hello and welcome to Dr. Mercola's cellular wisdom. I'm Ethan Foster, and I'm here with co-host
0:28.5	Alara Sky. Today we're focusing on what Dr. Mercola's mechanistic review reveals about
0:34.2	excessive L.A. intake, mitochondrial breakdown, gut imbalance, and why these pieces
0:40.4	converge in metabolic disease. A century ago, you barely ate L.A. Now it's everywhere. Soybean, corn,
0:48.3	canola, sunflower, safflower, peanut, cotton seed, grape seed, rice bran oils, and it's hidden in most processed
0:57.8	and restaurant foods. You've probably heard these are heart-healthy, yet L.A. is chemically
1:03.2	unstable and easily oxidized by heat, light, and oxygen. Instead of being cleanly burned,
1:09.9	it builds up in your tissues and quietly interferes with
1:12.9	energy production. Many of you report low energy, stubborn weight gain, or creeping insulin
1:18.2	resistance despite trying to eat well. The review points to LA as a major hidden driver. Unlike
1:24.6	more stable fats, LA doesn't just fuel you and move on. It gets stored,
1:29.1	accumulates, and sets the stage for oxidative damage that drains how much usable energy you can
1:34.4	generate. The damage starts in your mitochondria. L.A. gets incorporated into cardiolipin,
1:40.6	a distinctive structural fat in the inner mitochondrial membrane that helps hold the energy-producing
1:45.6	protein complexes together. Because LA is unstable, once it's in that position it's vulnerable
1:50.9	to oxidation, which weakens the membrane architecture and lowers adenosine triphosphate,
1:57.2	ATP output. The review describes a double hit, oxidative stress and reductive stress.
2:04.6	Oxidative stress means you're generating excess-free radicals. Reductive stress is the backup of
	...

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