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Masters in Business

Targeting Sickle Cell Disease (Sponsored Content)

Masters in Business

Bloomberg

Business, Entrepreneurship, Investing

4.42.2K Ratings

🗓️ 18 May 2025

⏱️ 16 minutes

🧾️ Download transcript

Summary

Terri Booker’s body burns with pain. She’s one of the 100,000 Americans living with sickle cell disease – a blood disorder that can cause severe pain, organ failure, and even premature death. The genetic condition came about to protect against malaria. Dr. William Hobbs leads clinical development for sickle cell disease at Vertex, and they are investigating multiple approaches to address the unmet needs that patients face. 

This episode of Targeting the Toughest Diseases is sponsored by Vertex Pharmaceuticals.

See omnystudio.com/listener for privacy information.

Transcript

Click on a timestamp to play from that location

0:00.0

Since you're a subscriber to this Bloomberg podcast, we thought you'd be interested in a six-episode

0:05.7

podcast called Targeting the Tuffest Diseases.

0:10.2

Produced by Vertex Pharmaceuticals and Bloomberg Media Studios.

0:14.2

It explores the innovative tools, methods, and unique philosophy vertex pharmaceuticals is using

0:20.7

to search for treatments for some of

0:22.8

humanity's most challenging diseases. Here's a recent episode.

0:29.1

And it's like if someone grabs your body and twists in the opposite direction with each hand,

0:38.5

it's like you can feel the pressure in your bones,

0:42.3

and you can just feel every part of your body is hurting.

0:47.4

20 years ago, during her sophomore year in college,

0:51.0

Terry Booker was hit with the worst pain of her life.

0:56.1

My legs were burning and then it just went up throughout my whole entire body to the point

1:04.0

where I was unconscious and I was put on life support.

1:09.2

I wasn't able to breathe on my own.

1:11.7

They told my mom I had kidney failure.

1:15.0

I had lung failure.

1:17.5

There was no clear path to treatment for her, just uncertainty.

1:21.6

They said, you just pray because we don't know what's going to happen to her.

1:28.6

What happened was she got better for a while.

1:32.9

But then the pain returned and she was back in the emergency room.

1:37.0

Her recurring visits to the ER seeking relief from the pain revealed a second problem,

1:42.1

not a medical one, a societal one.

...

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