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This is Scientific Americans' 60-second science.

I'm Karen Hopkins.

Pain. It's unpleasant. But what if pain could be rendered less painful, emotionally speaking?

Such uncoupling might not be entirely far-fetched, because researchers have located a set of neurons that seem to encode the feelings of hurt that accompany pain.

Pain is both a sensory and emotional experience.

Gregory Scherer, a pain expert at Stanford University.

Much of the research so far in the pain field has focused on the sensory aspect of pain perception,

and in particular how cells in our nerves are able to detect

stimuli that we perceive as painful.

But less is known about why most of us find pain so distressing.

So Scherer and his colleagues set out to first identify those brain cells that are active

when an animal experience is pain.

The researchers used a miniature microscope to look at the brains of

living mice. That technology was developed by Mark Schnitzer, who does neuroscience and applied physics

at Stanford. This microscope is small and light enough that it can be born on the head of an

adult mouse as the animal behaves in a natural manner. When these microscope-wearing mice were poked with a pin, or exposed to mild heat or cold,

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