meta_pixel
Tapesearch Logo
Log in
Discovery

Superbugs: Resistance Rising Part 3

Discovery

BBC

Science

4.31.2K Ratings

🗓️ 6 April 2026

⏱️ 30 minutes

🧾️ Download transcript

Summary

The rapid spread of antibiotic resistant bacteria is already claiming lives - and a far greater global crisis is on the horizon.

In this three part series for Discovery, reporter Roland Pease traces how we reached this point, uncovers the forces driving resistance ever faster, and meets the scientists racing to outpace evolving superbugs before our lifesaving medicines fail for good.

Episode 3 - Failed market. A successful new antibiotic must not only treat bacteria that resist existing therapies, it must be kept in reserve for only the hardest cases lest new kinds of resistance evolve, and yet it must pay back the developers' investment. No wonder several leading antibiotic companies have failed financially in the past 8 years. Is there a way to make antibiotic development pay?

Transcript

Click on a timestamp to play from that location

0:00.0

BBC Sounds, music, radio podcasts.

0:07.3

Their company's success helped build a nation.

0:10.9

The company is such a big part of Korea's economy.

0:13.5

But who are the family behind one of the world's tech giants?

0:17.2

They often say, look, we built the nation.

0:19.5

And without us, South Korea as it exists today,

0:22.6

would simply not be here. Inheritance, Samsung explores the real-life dramas of the Lee family

0:28.3

and their company. They are the equivalent of royalty. Listen first on BBC Sounds.

0:34.0

You know, I think it's underappreciated in some countries how desperate this crisis is

0:37.9

already. The bacterium we target is these carbapenum resistant introbacteracy. It's a very rare

0:44.0

infection in the UK. But if you go to Greece, they have in their ICU's a pathogen known as

0:49.8

Klebsiella. Already 90% of Klebsiella in those ICUs are resistant to carbopenoms, and carbopenoms are the last line of antibiotic defence. So these are patients in intensive care units with serious infections with no antibiotic options. 10 years ago, Greece didn't have CRE, so it can happen very quickly, and we're seeing this global spread. So there is a need to act early

1:12.0

in advance of the crisis really being an enormous medical and, of course, national problem.

1:17.8

That is, I'm afraid, not news. It's from an interview 11 years ago,

1:22.9

since when the medical crisis due to Carbopenum-resistant klebsiella has only grown worse. In 2017,

1:30.5

the World Health Organization put the bugs into the top critical category of priority pathogens

1:36.5

needing new antibiotics. My interview with Kenneth Hillen two years earlier was relevant. He was

1:43.3

the CEO of a company that was in

1:46.2

the final stages of testing the kind of new antibiotic the world needed. His company, a caogen,

1:52.5

was a small startup, hoping to fill a space vacated by the big drugs multinationals. I think the

1:58.8

challenge is that the economic model for antibiotics is fundamentally

2:02.7

broken. And the reason for that is, first, that for most infections, today's antibiotics can be

...

Please login to see the full transcript.

Disclaimer: The podcast and artwork embedded on this page are from BBC, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of BBC and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright © Tapesearch 2026.