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An early start here. It's time to kick off.

Your day. Morning!

What a line-up.

Oh, thanks very much. We do get some great guests on the show.

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And everything in between.

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Blue plaques on buildings in the UK mark places where important people lived, or important things happened.

The one on the red brick wall just behind me celebrates the birth of the age of antibiotics.

I'm not outside St Mary's Hospital in London where Alexander Fleming famously observed the lethal effects

of penicillium mould on cultures of bacteria almost 100 years ago. Rather, I'm outside the Dunn School

of Pathology in Oxford, where a decade later, Ernst Chain, Howard Florey and colleagues less

famously turned that observation into a lifesaver for medicine.

Or, as it says on the plaque, in this building, Howard Florey, Ernst Chain, Norman Heakley and colleagues,

first isolated and purified penicillin for the treatment of bacterial infection, 1938 to 1941.

Antibiotics have saved countless millions of lives since, but bacterial infections are

constantly fighting back. I'm Roland P's, and in the next three episodes of discovery from the BBC World Service,

I'll be hearing why health professionals worldwide are alarmed at the waning power of existing

antibiotics and the struggle to find new compounds to stock the pharmacy shelves. But first, let's go inside

...