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Up First from NPR

Strait Of Hormuz Tension, Trump Primaries in Indiana, Mifepristone Court Reprieve

Up First from NPR

NPR

Daily News, News

4.659K Ratings

🗓️ 5 May 2026

⏱️ 13 minutes

🧾️ Download transcript

Summary

President Trump launched “Project Freedom” to escort commercial ships through the Strait of Hormuz, but Iran immediately attacked the first vessels with missiles, drones and small boats on day one of the operation.
In Indiana, President Trump is pouring millions into state senate primaries to punish Republican lawmakers who blocked his push for new congressional maps, testing his hold over the party ahead of the midterms.
The Supreme Court has granted the abortion pill mifepristone a one-week reprieve, allowing it to continue being mailed while a major legal challenge from Louisiana plays out.

Want more analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Andrew Sussman, Megan Pratz, Diane Webber, Mohamad ElBardicy and Jan Johnson.

It was produced by Ziad Buchh and Nia Dumas.

Our director is Kaity Kline.

We get engineering support from Neisha Heinis. Our technical director is Carleigh Strange.

And our Supervising Senior Producer is Vince Pearson.

(0:00) Introduction
(01:53) Strait Of Hormuz Tension
(05:54) Trump Primaries in Indiana
(09:45) Mifepristone Court Reprieve

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Transcript

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0:00.0

The U.S. and Iran traded fire Monday as the U.S. plan to reopen the Strait of Hormuz began.

0:08.4

Iran has launched multiple cruise missiles, drones, and small boats, as ships we are protecting.

0:13.9

Does this mean the ceasefire is over?

0:15.8

I'm Lela Falded. That's A. Martinez, and this is up first from NPR News.

0:22.0

In Indiana, President Trump is working hard to primary Republican state senators who defied him on redistricting.

0:29.4

We've never had Washington meddle into our elections like they have this time.

0:33.4

How much poll does the president still have inside his own party?

0:36.3

And the Supreme Court is allowing the abortion pill Miffapristone to be sent by mail for one more week while a legal challenge from Louisiana moves forward.

0:44.6

What happens after that?

0:46.3

Stay with us.

0:46.8

We've got all the news you need to start your day.

1:00.3

Some commercial ships have left the Strait of Hormuz under a major U.S. operation to reopen the waterway.

1:13.6

The U.S. and Iran traded fire on Monday, threatening a month-old ceasefire. The fighting erupted when the U.S. launched the operation, but Pentagon Chief Pete Hegeseth insisted this morning that the ceasefire is not over.

1:23.3

We prefer this to be a peaceful operation, but are locked and loaded to defend our people, our ships, our aircraft, and this mission without hesitation.

1:32.9

We're joined by NPR National Security correspondent, Greg, Myrie, Greg. I mean, the focus for the past month has been these halting peace efforts, so are we now all heading back to more fighting?

1:38.4

Well, at this point, we can say we did see a major change in direction yesterday.

1:45.7

Over the past month, the U.S. and Iranian naval blockades have kept the region very tense, lots of back and forth about negotiations, but relatively quiet. Now we see the U.S. was using this time to

1:52.4

prepare for this operation. And there was a lot of confusion initially yesterday, reports of

1:58.0

shooting in and around the Strait of Hormuz of the U.S. and commercial ships

2:02.9

on the move. It was hard to make sense of it. We finally got some clarity when Admiral Brad

2:08.3

Cooper, the head of Central Command in the Middle East, held a hastily arranged conference call

2:13.3

with U.S. journalists in Washington. So how did Admiral Cooper explain the operation?

...

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