Tonight on 360, investors brace for impact again with huge new tariffs just hours away and higher prices soon to follow.

Also tonight, where this all leads in money, jobs, and America's role in the world, John Bolton, Professor Scott Galloway and Senator Elizabeth Warren join us.

Plus some potentially good news on Alzheimer's. A startling new study shows a possible

path to preventing cognitive decline. Things you can do starting tonight, Dr. Sanjay Gupta has the

latest. Good evening. Thanks for joining us. And starting at midnight, get ready for the price of things you

buy to go up even more. In some cases, prices may nearly double. Just four hours from now, the tariff on goods imported

from China, which Americans, not Chinese pay, will rise another 50 percent to a staggering

104 percent. The president, as you know, said this would happen at Beijing did not roll back

its own retaliatory rate increases for the 34 percent bump Trump imposed on Chinese imports last week.

And today, when it became clear that China would not blink, the market started down.

Well, the selling began just moments after the White House announced the deadline had passed.

The Dow lost a bit less than 1%. The NASDAQ, more than 2%, the S&P 500 down a percent and a half.

Now, investors are dealing with the China News and the start also at midnight tonight of Canada's

25 percent tariff on American-made cars, which itself is retaliation for the president's corresponding 25% levy on Canada imposed last week.

Those tariffs have already led to the shutdown of assembly lines on both sides of the border

and the idling of hundreds of jobs.

The administration, though, is pressing ahead, especially on China.

The president was asked and answered this yesterday.

He said he's not considering an extension or delay.

I spoke to him before this briefing.

That was not his mindset.

He expects that these tariffs are going to go into effect.

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