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The Human Upgrade with Dave Asprey

Still Fasting in 2025? Here’s How to Make It Work Better : 1315

The Human Upgrade with Dave Asprey

Dave Asprey

Fat, Health & Fitness, Meditation, Biohacking, Lifestyle, Diet, Science, Self-improvement, Fasting, Nutrition, Hacking, Fitness, Brain, Wellness, Education

4.67.3K Ratings

🗓️ 15 August 2025

⏱️ 61 minutes

🧾️ Download transcript

Summary

How do you activate your body’s natural repair system? How can you hack stem cells for faster recovery, brain optimization, and peak human performance? This episode reveals how to trigger stem cell release, direct them to the right tissues, and stack biohacking tools for maximum regeneration. You’ll learn science-backed strategies for boosting mitochondria, enhancing neuroplasticity, and extending longevity through targeted supplements, fasting, and functional medicine techniques. 


Watch this episode on YouTube for the full video experience: 

https://www.youtube.com/@DaveAspreyBPR 


Host Dave Asprey talks with Christian Drapeau, a leading stem cell scientist and founder of STEMREGEN. Christian’s decades of research have transformed our understanding of how stem cells repair the body, reverse damage, and amplify performance. He shares practical protocols to mobilize stem cells, improve microcirculation, and reduce inflammation so your body heals faster, functions better, and stays younger for longer. 


You’ll learn: 

• How stem cells rebuild muscle, brain, and organ tissue for optimal human performance 

• Why fasting rejuvenates bone marrow and increases stem cell effectiveness 

• The synergy between PEMF, vibration therapy, cold therapy, and stem cell activation 

• How microcirculation and inflammation control improve longevity and recovery 

• The best supplements and nutrients to support mitochondria and stem cell health 

• How to stack nootropics, ketosis, and brain optimization tools for lasting energy and focus 


This is essential listening for anyone serious about biohacking, longevity, human performance, mitochondria health, neuroplasticity, functional medicine, fasting protocols, supplements for recovery, brain optimization, smarter not harder healing, metabolism upgrades, cold therapy stacks, and next-level physical and cognitive resilience 


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade is the top podcast for people who want to take control of their biology, extend their longevity, and optimize every system in the body and mind. Each episode features cutting-edge insights in health, performance, neuroscience, supplements, nutrition, hacking, emotional intelligence, and conscious living. 


Episodes are released every Tuesday, Thursday, and Friday (audio-only) where Dave asks the questions no one else dares, and brings you real tools to become more resilient, aware, and high performing. 


Keywords: STEMREGEN, biohacking, natural stem cell activation, human performance, longevity, mitochondria, neuroplasticity, fasting, bone marrow rejuvenation, functional medicine, supplements, brain optimization, metabolism, cold therapy, microcirculation, nootropics, ketosis, smarter not harder, recovery hacks 


Resources:  

• STEMREGEN Website: https://www.stemregen.co/dave for 20% off your first order.  

• Dave Asprey’s Website: https://daveasprey.com 

• Danger Coffee: https://dangercoffee.com/DAVE15 

• Dave Asprey’s BEYOND Conference: https://beyondconference.com 

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated 

• Upgrade Collective: https://www.ourupgradecollective.com 

• Upgrade Labs: https://upgradelabs.com 

• 40 Years of Zen: https://40yearsofzen.com 


Timestamps: 

0:00 — Trailer 

1:00 — Why Some People Regenerate Better 

1:52 — Testing Stem Cell Levels 

2:58 — Natural Stem Cell Function 

3:59 — Exercise & Stem Cell Response 

5:13 — Tissue Turnover & Regeneration 

7:03 — Bone Marrow Production 

8:16 — Fasting & Bone Marrow 

9:33 — Nutrition for Bone Marrow 

11:14 — Traditional Meets Modern Science 

12:58 — Training Bone Marrow 

13:57 — Stem Cells as Repair System 

34:20 — Stem Cells & Brain Injury 

47:01 — Inside STEMREGEN Products 

55:41 — Stress, Cortisol & Stem Cells 

58:12 — Final Recommendations 

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Transcript

Click on a timestamp to play from that location

0:00.0

The entire body is constantly going through a process of tissue turnover.

0:04.0

You get a new skin every month, a new liver every two, three years.

0:07.0

Cells have a specific lifetime.

0:09.0

They are replaced and they're replaced by stem cells.

0:12.0

Stem cells have been doing their job and repairing in your body since the day you're born.

0:16.0

Christian Drepos is a pioneering stem cell scientist whose groundbreaking research is

0:20.0

redefining how we heal and regenerate the body.

0:22.7

He's not just advancing science. He's unlocking the body's ability to repair itself from within.

0:27.7

The ability of stem cells to migrate and multiply increases after fasting. So you take stem cells before

0:33.7

fast and after fasting and you see that they're more effective which means they

0:37.8

act as younger stem cells the more we dive into stem cell research the more we need to

0:42.8

realize it's like your immune system any body fluid is likely to have stem cells

0:47.3

they are really everywhere and they are the body's repair system the idea is

0:51.8

we're making stem cells in our marrow. How do we influence the quality

0:56.9

of our bone marrow so that we can make more stem cells? You're listening to the Human Upgrade

1:02.4

with Dave Asprey.

1:07.4

Hey guys, quick reminder. If you're listening to this on your favorite audio podcast app and you haven't been over to my YouTube channel, check it out. Just search for the human upgrade or find me under Dave Asprey BPR. I post full video versions of every episode and a bunch of other cool content outside the pod. It's a great way to go deeper into the content and connect with other biohackers like you.

1:28.9

So leave a comment for me, yeah, I'm actually going to read them and poke around while you're

1:32.0

there. There is a lot of stuff specifically for you. It really helps and it means a lot to me.

1:38.5

Why do some people regenerate and other people just break down? I would say it comes down to

1:43.4

how many stem cells you have

1:45.0

in your bloodstream. And because this is something that is interesting. If you look at your last

...

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