Hey all, welcome back to the Real Life Pharmacology podcast. On this episode, I'm going to cover

SSRI adverse effects, as well as sum up some of the most important things you need to know

for practice and for your board exams and pharmacology exam. But before we get to the podcast, be sure to check out real-life pharmacology.com.

Get your free 31-page PDF on the top 200 drugs.

Great study guide, great refresher, whether you're out in practice or you're a student trying

to learn more about pharmacology.

Again, simply an email will get you access to that free 31-page

PDF on the top 200 drugs. All right, let's get into the podcast today. S-SRIs can cause

sexual dysfunction as a class-type effect. Generally, the highest risk agents here are peroxatine, probably number one.

Certraline also is up there a little bit. But again, all the SSRIs can contribute to that.

In patients that experience this adverse effects, and they're like, no way, I'm not taking another

SSRI. It was too problematic, too annoying, too bothersome. Usually the go-to-antidpressants to consider

are bupropriion and myrtazapine, which really avoid or minimize or reduce

the serotonergic type pathway,

which is theorized to contribute

to some of that sexual dysfunction.

Okay.

So again, sexual dysfunction,

definitely something you want to ask about,

not necessarily the most comfortable to ask about,

but it can be one of the more common reasons why patients discontinue their SSRI.

And they may not want to tell you about it as well. So really important to assess that.

...