Sep 06 2024 This Week in Cardiology
This Week in Cardiology
Medscape Podcasts
4.9 • 963 Ratings
🗓️ 6 September 2024
⏱️ 30 minutes
🧾️ Download transcript
Summary
Feedback on ABYSS and beta-blockers, more ESC recap, including SHAM-PVI, FINEARTS-HF, and RESHAPE HF2 trials are the topics John Mandrola, MD, discusses in today's podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I. Feedback on ABYSS
Setbacks After Stopping Beta-Blockers
https://www.medscape.com/viewarticle/setbacks-after-stopping-beta-blockers-2024a1000fv7
Beta-Blockers Post-MI? No for Me, Even After the ABYSS Trial
https://www.medscape.com/viewarticle/beta-blockers-post-mi-no-me-even-after-abyss-trial-2024a1000fva
- ABYSS trial https://www.nejm.org/doi/full/10.1056/NEJMoa2404204
- REDUCE AMI https://www.nejm.org/doi/full/10.1056/NEJMoa2401479
- QOL paper REDUCE AMI https://doi.org/10.1093/ehjcvp/pvae062
- Atenolol ED paper 10.1016/j.ehj.2003.08.016
II. SHAM-PVI
- JAMA SHAM-PVI paper https://jamanetwork.com/journals/jama/article-abstract/2823283
- Gupta QOL paper https://pubmed.ncbi.nlm.nih.gov/33952593/
III. FINEARTS HF
Finerenone Benefits Heart Failure With Preserved EF
https://www.medscape.com/viewarticle/finerenone-benefits-heart-failure-preserved-ef-2024a1000fza
Topline Finerenone Results Point to Advance in Heart Failure
https://www.medscape.com/viewarticle/topline-finerenone-results-point-advance-heart-failure-2024a1000fq2
- FINEHEARTS -HF NEJM https://www.nejm.org/doi/full/10.1056/NEJMoa2407107
- FIDELIO-DKD https://www.nejm.org/doi/full/10.1056/NEJMoa2025845
- FIGARO-DKD https://www.nejm.org/doi/full/10.1056/NEJMoa2110956
- Why Have We Not Been Able to Demonstrate Reduced Mortality in Patients With HFmrEF/HFpEF? https://doi.org/10.1016/j.jacc.2024.08.033
IV. RESHAPE HF
TEER in Functional MR: Data Deluge, but No Easy Answers
https://www.medscape.com/viewarticle/teer-functional-mr-data-deluge-no-easy-answers-2024a1000fvg
- Mitra FR https://www.nejm.org/doi/full/10.1056/NEJMoa1805374
- COAPT https://www.nejm.org/doi/full/10.1056/NEJMoa1806640
- RESHAPE- HF2 https://www.nejm.org/doi/full/10.1056/NEJMoa2314328
- RESHAPE Subgroup paper https://doi.org/10.1016/j.jacc.2024.08.027
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Questions or feedback, please contact news@medscape.net
Transcript
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| 0:00.0 | You're listening to this week in cardiology from the heart |
| 0:03.4 | org medscape cardiology this podcast is intended for health care |
| 0:07.6 | professionals only any views expressed are the presenters own and do not |
| 0:11.2 | necessarily reflect the views of WebMD or Medscape. |
| 0:15.1 | You can now access the latest in medical news on your Amazon Alexa-enabled device. |
| 0:19.7 | Join me, Perry Wilson, every weekday morning for Medscape Medical Minute where I highlight the top |
| 0:24.7 | medical stories of the day. |
| 0:26.5 | To add Medscape Medical Minute to your flash briefing, search for Medscape Medical Minute on Amazon |
| 0:31.3 | and click enable or open the Amazon Alexa app go to |
| 0:34.4 | skills search for Medscape Medical Minute and click enable then say |
| 0:38.8 | Alexa what's the news or Alexa what's my flash briefing I hope you'll join us. |
| 0:45.2 | Hi everyone this is John Mandrola from the heart.org medscape |
| 0:50.4 | and this is this week in cardiology for September 6, 2024. This week some brief feedback on the |
| 0:57.7 | abyss trial and beta blockers, a more ESC recap including the sham PBI fine hearts h f and more ESC recap, C.S.C. recap, |
| 1:05.0 | including the Sham PBI, Fine Hearts H.F. trial. |
| 1:06.7 | And it will take a couple of weeks at least to recap all of the trials |
| 1:11.7 | at the ESC meeting. |
| 1:14.3 | First topic is some feedback on Beta Blockers and the Abyss trial. |
| 1:19.4 | Recall that Abyss was Beta Blocker discontinuation at one year after my in patients had a preserved |
| 1:25.7 | EF. The trial, which compared continuation versus discontinuation at one year, was-ish for the continuation group. |
| 1:36.3 | But this positive finding was driven by increased hospitalizations into this continuation |
| 1:42.3 | group, mostly for angiography. |
... |
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