Sarcoidosis
Medgeeks with Andrew Reid
Medgeeks
4.8 • 997 Ratings
🗓️ 10 February 2020
⏱️ 15 minutes
🧾️ Download transcript
Summary
A 39 year old female presents to you for cough that she has had for 7 months. It is a dry cough that she has assumed is related to her allergies. Nothing makes this cough go away. She takes no medications, other than Zyrtec daily and has no past medical history. Over the past 2-3 weeks she develops, fatigue, night sweats and even reports a fever.
It seems this may be a bit more than simple allergies. You wisely obtain a CXR to evaluate this chronic cough with now constitutional symptoms and you believe you have your answer when you see the finding of bilateral hilar adenopathy.
Now, how to manage it? What tests need to be ordered further? What advice do you give this patient? What are we going to do?
On today's podcast we dive into the curious and fascinating disease known as sarcoidosis.
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Transcript
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| 0:00.0 | A 39-year-old female presents to you for a cough that she has had for seven months. |
| 0:05.2 | It's a dry cough that she has assumed is related to her allergies. |
| 0:09.2 | Nothing makes this cough go away. |
| 0:11.0 | She takes no medications other than Zyrtec daily and has no past medical history. |
| 0:15.6 | Over the past two to three weeks, she has started to develop fatigue, night sweats, and even reports of fever one week ago. It seems this may be a bit more than simple allergies. |
| 0:26.1 | You wisely obtain a chest x-ray to evaluate this chronic cough with now constitutional symptoms and you believe you have your answer when you see the finding of bilateral high law |
| 0:36.8 | adenopathy. Now how to manage it, what tests need to be ordered further? What advice do you give to this patient? What are we going to do? |
| 0:46.5 | On today's podcast, we dive into the curious and fascinating disease known as sarcoidosis. Welcome, welcome everybody. My name is Eric Gordon and this is the med geeks |
| 1:14.2 | podcast. I'm glad you're with us today. We are talking about sarcoidosis. |
| 1:18.9 | Now if you're like me you might be saying to yourself, self what what exactly is Sarcoidosis again? |
| 1:24.4 | Isn't it kind of like lupus? |
| 1:26.4 | Isn't it something with the lungs? |
| 1:27.9 | What's going on? |
| 1:28.9 | Today we're going to review all that and more. |
| 1:31.5 | To start off, let's do a little bit of background on sarcoidosis. This is a systemic disease of unknown cause characterized by the formation of granulomas. And these granulomas pop up virtually anywhere in the body |
| 1:46.8 | is possible, but the most common places are the lung, the intrathoracic lymph nodes, skin, |
| 1:52.4 | eyes, and other places that we'll talk about. |
| 1:54.9 | The hypothesized mechanism is that this is an exaggerated immune response to mycobacteria infection or another environmental antigen and it's believed to have a genetic predisposition. |
| 2:08.7 | So first and second degree relatives of patients with sarcoidosis have an increased risk and the estimated |
| 2:14.8 | heritability of sarcoidosis is 66% based on a Danish and Finnish twin |
| 2:21.0 | study that they looked at 210 pairs of twins. |
| 2:24.0 | They've done big studies looking at people with sarcoidosis |
... |
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