4.8 • 2.4K Ratings
🗓️ 5 November 2025
⏱️ 55 minutes
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Register for the Austin listener meetup
Sam Altman makes his second appearance on the show to discuss how he's managing OpenAI's explosive growth, what he's learned about hiring hardware people, what makes roon special, how far they are from an AI-driven replacement to Slack, what GPT-6 might enable for scientific research, when we'll see entire divisions of companies run mostly by AI, what he looks for in hires to gauge their AI-resistance, how OpenAI is thinking about commerce, whether GPT-6 will write great poetry, why energy is the binding constraint to chip-building and where it'll come from, his updated plan for how he'd revitalize St. Louis, why he's not worried about teaching normies to use AI, what will happen to the price of healthcare and hosing, his evolving views on freedom of expression, why accidental AI persuasion worries him more than intentional takeover, the question he posed to the Dalai Lama about superintelligence, and more.
Recorded live at the Progress Conference, hosted by the Roots of Progress Institute. Special thanks to Big Think for the video production.
Read a full transcript enhanced with helpful links, or watch the full video on the new dedicated Conversations with Tyler channel.
Recorded October 17th, 2025.
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Photo Credit: Jeremi Rebecca
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| 0:00.0 | Hi, listeners, this is Tyler. |
| 0:06.6 | Please mark your calendars for Friday, January 9th. |
| 0:10.0 | We're hosting a CWT listener meetup in Austin, Texas at Parkside on East 6th Street. |
| 0:18.0 | This is your chance to connect with fellow fans and meet me and also the entire |
| 0:22.7 | CWT team in person and to enjoy some great conversation over light refreshments. We'll have a |
| 0:29.9 | Q&A session plus plenty of time to mix and mingle. Space is limited in filling up fast, so click |
| 0:36.6 | the link in the show notes to register now. |
| 0:39.4 | It's first come, first serve, and plus ones are absolutely welcome. |
| 0:43.7 | Just make sure they register at the link as well. |
| 0:46.9 | Hope to see you there. |
| 0:53.3 | Conversations with Tyler is produced by the Mercatus Center at George Mason University, |
| 0:58.5 | bridging the gap between academic ideas and real-world problems. |
| 1:02.7 | Learn more at Mercadis.org. |
| 1:04.8 | For a full transcript of every conversation enhanced with helpful links, |
| 1:09.6 | visit Conversationswith with Tyler.com. |
| 1:17.2 | Hello, Sam. Happy to do this with you. Excited to do it again. Now, the last two months or so, |
| 1:22.5 | there have been so many deals involving OpenAI, and I'm not even talking about the |
| 1:26.1 | globetrotting. A lot of them are local, |
| 1:27.8 | or there's new product features, such as Pulse. Presumably, you are productive to begin with. |
| 1:33.4 | How is it that you manage to up your productivity to get all this done? |
| 1:37.6 | I mean, a lot of, I don't think there's like one single takeaway other than I think you always |
| 1:42.6 | are, people are almost never allocate their time as well as |
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