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EPIDEMIC with Dr. Celine Gounder

S1E63 / Chasing the Cure / David Fajgenbaum

EPIDEMIC with Dr. Celine Gounder

KFF Health News and Just Human Productions

Society & Culture, #Eradication, Medicine, #Covid, Science, Life Sciences, #Sarscov2, Documentary, #Coronavirus, #Covid19, Health & Fitness, #Smallpox

4.61K Ratings

🗓️ 25 February 2021

⏱️ 23 minutes

🧾️ Download transcript

Summary

"When we think about a virus we don't think as much about the immune response to the virus but it is just so, so critical." -David Fajgenbaum Where do treatments come from when there's a new disease like COVID-19? The vast majority of drugs prescribed to treat COVID during the pandemic are actually old drugs. Some of the most effective have been around for as much as 70 years. In this episode of EPIDEMIC, we’re going to hear how David Fajgenbaum's quest for a treatment for his rare disease is helping find effective treatments for COVID — and other diseases — in surprising places. This podcast was created by Just Human Productions. We're powered and distributed by Simplecast. We're supported, in part, by listeners like you. #SARSCoV2 #COVID19 #COVID #coronavirus

Transcript

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0:00.0

The challenge here with COVID is that there's not going to be a one-size-fits-all drug.

0:13.4

It's going to be a drug for a very specific population in a very specific time.

0:18.3

So many of us, when we think about a virus, we think about the virus, and we don't think

0:22.9

as much about the immune response to the virus, but that part of it is just so so critical.

0:30.0

You're listening to Epidemic, the podcast about the science, public health, and social

0:43.7

impacts of the coronavirus pandemic.

0:46.4

I'm your host, Dr. Saline Gounder.

1:00.5

David Faganbaum's life changed when his mom got sick. His mother was diagnosed with brain cancer

1:08.4

when he was in college, and that set him on a path into medicine. Watching her battle

1:14.8

both inspired me to want to help patients like her and watching her doctors inspired me to want

1:21.3

to want to be more like them. I wanted to dedicate my life towards trying to find solutions for

1:26.5

patients like my mom. David's mom passed away not long after her diagnosis.

1:32.0

That experience for me just put it very clearly in front of me that you can do all the right things,

1:40.4

you can go to all the right doctors and take all the right medications, and things still don't

1:45.2

always work out the way that you would hope that they would. But that experience only motivated David

1:51.1

more. He graduated college and went to medical school at the University of Pennsylvania.

1:56.6

He decided to become an oncologist.

1:59.2

And so if you fast forward a few years to my third year of med school, I was on track and really

2:05.9

hopeful about being able to help patients like my mom, when out of nowhere I became the patient

2:10.8

myself. That's when his life changed again. When I was hospitalized, I was even in the intensive

2:16.6

care unit spent almost six months hospitalized with liver, kidney, bone marrow dysfunction.

2:22.0

I actually even had my last rights read to me. It took 11 weeks before the doctors could tell David

...

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