Research Spotlight: Inflammaging is the Future of Skincare and Longevity with Dr Ekta Yadav

Skincare Anarchy

Ekta et al.

Fragrance, Fashion, Entertainment News, Fashion & Beauty, Education, Entrepreneurship, Skincare, Skin, News, Makeup, Style, Dermatology, Self-improvement, Beauty, Arts

4.2 • 2K Ratings

🗓️ 27 May 2025

⏱️ 10 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

In this special episode of Skin Anarchy, host Dr. Ekta Yadav celebrates a milestone moment—her latest mini review, Inflammation and Aging: The Skin Inflammasome in the Context of Longevity Science, has been published in the Journal of Cellular Immunology. This episode offers listeners a deep but accessible dive into the mechanisms that link chronic inflammation, skin health, and the biology of aging.

Dr. Yadav unpacks the concept of “inflammaging,” explaining how low-grade, persistent inflammation accelerates skin aging and predisposes us to a host of conditions—from acne and psoriasis to pigmentation disorders. Central to this is the NLRP3 inflammasome, a cellular sensor that responds to both internal stress and external insults. But the conversation doesn’t stop at surface-level inflammation—it zooms out to show how NAD+ depletion, mTOR signaling, sirtuin activity, and cellular senescence all play a role in the skin’s aging clock.

Listeners will get a taste of the therapeutic landscape too—from the promise of repurposed drugs like metformin and rapamycin to the caution needed around immune modulation. Dr. Yadav also weaves in emerging research on gut-skin interactions and psychoneuroendocrine links, emphasizing the systemic nature of skin health in the context of longevity.

If you’re curious about the future of aging, biohacking, or the real science behind graceful skin longevity, this episode is a must-listen. Tune in to learn what’s next in skin biology—and why inflammation is more than just skin deep.

Read the full article HERE.

To learn more about Dr. Ekta, visit her social media.

Don’t forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform. Reach out to us through email with any questions.

Hosted on Acast. See acast.com/privacy for more information.

Transcript

Click on a timestamp to play from that location

0:00.0	Hey guys, welcome to a very special segment on Skin Anarchy.
0:04.9	I'm very excited to announce that we have been published in the Journal of Cellular Imminology for our mini review.
0:11.7	Our mini review entitled Inflammation and Aging, the Skin Inflamazome in the context of longevity science.
0:18.8	This mini review is very special to me because I am really starting to dive deeper into the world of longevity medicine.
0:25.6	There has been so much buzz in the media about longevity and just what it means.
0:29.6	I know a lot of you have seen things by individuals like Dr. Sinclair, you know,
0:34.6	and then there's all these leading experts out there that are really
0:38.1	voicing their opinions about this, about their medical opinions, whether they're MDs, PhDs,
0:43.5	physician scientists, everyone's really kind of chiming in right now because I think the frontier
0:47.8	truly is longevity. Let's be honest. All of us, I think, innately know that. I mean, look around
0:53.5	how many of you know somebody that's on an NAD supplement us, I think, innately know that. I mean, look around how many of you know
0:54.5	somebody that's on an NAD supplement already? You know, NAD supplements just became a thing. The
0:59.9	science just got validated. And here we all are already translating it to real products and real
1:06.0	innovations that can benefit our daily lives. And so this is an incredibly exciting time for medicine, science,
1:13.7	all of those things. So I want to actually dive into the review. When you guys check it out,
1:18.1	you'll see what I mean, but what I try to do in this review is kind of bring all that science
1:23.6	together that's out right now. It's floating around. There's been very like kind of preliminary
1:28.4	level papers published about it. I'm not going to lie. Longevity medicine is an ocean, but we are
1:34.1	far from understanding, you know, just like we don't know much about the actual ocean, we don't
1:38.7	know much about longevity medicine. You know, it's very, very similar in that way. So whatever is out
1:43.3	there, we've tried our best to compile that information in a very short, bite-sized amount so that you get a hit of everything.
1:50.0	And it creates this wonderful landscape for you to understand, like, this is what's going on, this is what we found out, here's where we are right now.
	...

Please login to see the full transcript.

Previous episode | Next episode

Disclaimer: The podcast and artwork embedded on this page are from Ekta et al., and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Ekta et al. and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.