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The a16z Show

Reid Hoffman on AI, Consciousness, and the Future of Humanity

The a16z Show

a16z

Science, Innovation, Business, Entrepreneurship, Culture, Disruption, Software Eating The World, Technology

4.41.1K Ratings

🗓️ 20 October 2025

⏱️ 53 minutes

🧾️ Download transcript

Summary

Reid Hoffman has been at the center of every major tech shift, from co-founding LinkedIn and helping build PayPal to investing early in OpenAI. In this conversation, he looks ahead to the next transformation: how artificial intelligence will reshape work, science, and what it means to be human. In this episode, Reid joins Erik Torenberg and Alex Rampell to talk about what AI means for human progress, where Silicon Valley’s blind spots lie, and why the biggest breakthroughs will come from outside the obvious productivity apps. They discuss why reasoning still limits today’s AI, whether consciousness is required for true intelligence, and how to design systems that augment, not replace, people. Reid also reflects on LinkedIn’s durability, the next generation of AI-native companies, and what friendship and purpose mean in an era where machines can simulate almost anything. This is a sweeping, high-level conversation at the intersection of technology, philosophy, and humanity.

Transcript

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0:00.0

This is actually one of the things I think people don't realize about Silicon Valley.

0:03.6

You start with what's the amazing thing that you can suddenly create?

0:08.0

Lots of these companies, and you go, what's your business ball?

0:10.1

I don't know.

0:11.5

They're like, yeah, we're going to try to work it out.

0:13.6

I can create something amazing here.

0:16.1

And that's actually one of the fundamental, call it the religion of Silicon Valley

0:19.6

and the knowledge of Silicon Valley

0:21.2

that I so much love and admire and embody.

0:25.2

Reid Hoffman has spent decades helping shape how we connect, work, and build online from PayPal and

0:30.1

LinkedIn to open AI and beyond. In this episode, I'm joined by Reed and A16Z general partner

0:36.0

Alex Rampel to talk about how AI is reshaping

0:39.0

not just work but what it means to be human.

0:41.6

We discuss how far current AI models can go, what's holding them back, and why the next

0:46.2

breakthroughs will likely come from places Silicon Valley isn't even looking.

0:50.7

We also talk about friendship, meaning, and how to stay grounded in an era of exponential change

0:55.5

when our tools might soon think, reason, and even feel alongside us.

1:00.0

Let's get into it.

1:03.3

Reid, welcome things and scene podcast.

1:05.1

It's great to be here.

1:06.4

So, Reid, you're one of the most successful Web 2 investors of that era, Facebook, LinkedIn, obviously, which you co-created, Airbnb, many, many others, and you had several frameworks that helped you do that, one of which was the Seven Deadly Sins, which we talk about often in love. As you're thinking about AI investing, what's a framework worldview that you take to your AI investing? So obviously, we're all looking through a glass darkly, looking through a fog with strobe lights that, you know, are hard to understand what's going on. So we're all navigating this new universe. So I don't know if I have as Christopher from it. The seven deadly stins still work because that's a question of what is psychological infrastructure across all 8 billion plus human beings.

1:46.1

But I'd say there's a couple things.

...

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