Recent Hyponatremia Correction Rate Data Is Becoming Harder to Ignore
Hospital and Internal Medicine Podcast
Gil Porat, M.D., FACP, CPT
4.7 • 587 Ratings
🗓️ 20 April 2026
⏱️ 10 minutes
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| 0:00.0 | It's starting to take real effort to ignore the latest data on hyponetremia treatment rates. |
| 0:05.9 | It's like trying to ignore the pop-up ads after your teenage son was home when you were out to dinner and he was using the computer all evening. |
| 0:13.4 | I don't want to give definitive advice on this podcast. |
| 0:19.4 | And I'm going to use a caveat here that I'm not telling anybody |
| 0:23.4 | to change their practice. This undoubtedly will get you thinking about what you're doing in your |
| 0:28.8 | practice. But how you practice is not up to me. As a teenager once responded to me, as I was |
| 0:35.8 | trying to talk about getting a Taco Bell tattoo, |
| 0:39.0 | I'll do me, you do you. |
| 0:42.2 | But as many of you have been keeping up on, there are several recent studies that challenge |
| 0:48.1 | conventional guidelines and challenge conventional thinking. |
| 0:52.7 | Now after you hear the recent data, you have to decide |
| 0:56.0 | how long do you want to hold a human in a hyponatremic state, |
| 1:02.0 | which is what you're doing if you're too slow in the rate of correction of hyponatremia. |
| 1:09.0 | But I also caution that I am not saying that rapid correction is the |
| 1:14.0 | best in every situation because it is going to be a nuanced answer as we figure it out more and |
| 1:20.4 | more for different patient populations. But why don't we start with the article titled |
| 1:26.6 | Sodium Correction Rates and Associated |
| 1:29.6 | Outcomes Among Patients with Severe Hyponatremia? |
| 1:34.0 | This was a retrospective study, and it's from the Annals of Internal Medicine from |
| 1:39.7 | January 27th, 2026. And what the conclusion of the study is, if you quote it, is faster sodium |
| 1:49.6 | correction is associated with lower risk for 90-day death or delayed neurologic events. Treatment |
| 1:58.4 | guidelines should be re-examined. And in this study, a slow correction at |
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