REBOOT #151 Anaphylaxis

The Curbsiders Internal Medicine Podcast

Health & Fitness, Medicine, Science, Higher Education, Education

4.8 • 3.1K Ratings

🗓️ 30 March 2022

⏱️ 41 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Recognize common presentations of anaphylaxis and stop under-treating this deadly allergic reaction with tips from Dr. Olajumoke Fadugba, Assistant Professor of Medicine, University of Pennsylvania! We review the basic pathophysiology and the standard criteria for diagnosing anaphylaxis, treatment basics, the primary importance of epinephrine, and the utility of adjunctive therapies. Also included are great tips on counseling patients about auto-injectable epinephrine, and a reminder not to panic…even when you inject your own thumb?! Original show notes here.

Credits

Producer, infographic, and cover art: Emi Okamoto MD
Hosts: Matthew Watto MD, FACP; Stuart Brigham MD, Emi Okamoto MD
Editor: Matthew Watto MD, FACP
Guest: Olajumoke Fadugba MD
Special thanks to Sarah Phoebe Roberts MPH for booking!

Show Segments

Intro and disclaimer
Guest one-liner, book recommendation, advice to fellows and trainees
Case of anaphylaxis with mucocutaneous and GI symptoms
Anaphylaxis (IgE mediated mast cell action) vs anaphylactoid (non-IgE mediated mast cell activation; e.g. contrast allergy, vancomycin)
Vancomycin and non-IgE mediated reactions
Common presentations of anaphylaxis and the three diagnostic criteria
Biphasic reactions and predicting severity
Counseling patients on the use of epinephrine
Stuart’s thumb question
Adjuvant medications: antihistamines and corticosteroids
Are there any contraindications to epinephrine use?
Use of tryptase levels when the diagnosis of anaphylaxis is uncertain
Outro

Sponsor

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Transcript

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0:00.0	Hey listeners, we're so excited for April 2022 because we're going to be attending S.
0:05.7	Jim and Orlando Florida and ACP's internal medicine beating in Chicago.
0:10.6	So we hope to see lots of you there.
0:12.6	Plus, we have some really great episodes that we recorded already.
0:16.2	A cute pancreatitis is coming out next week.
0:18.8	We have episodes on hepatitis C and a two-part series on inpatient diabetes.
0:23.8	So don't miss those all coming to you in April 2022.
0:27.5	But for now, enjoy this curbsiders classic that we recorded at ACP 2019.
0:33.5	Enjoy.
1:03.5	Welcome back to the curbsiders.
1:10.5	Well, hello Matthew.
1:12.5	Hi Stuart, this is weird, I'm in the same room as you recording again.
1:15.5	That's great.
1:16.5	Which hasn't happened for quite a while.
1:18.5	Yeah, I'm a little shy.
1:21.5	And with us, we have a new producer, Emmy Okamoto.
1:26.5	Hello curbsiders.
1:29.5	Thank you Emmy for producing this episode.
1:31.5	Actually, before Stuart berates the audience, why don't you tell them what this episode is going to be about?
1:37.5	Yeah, today we're discussing anaphylaxis.
1:40.5	So don't be scared, but be ready to treat with epinephrine.
1:44.5	We'll be going over the treatment, how to recognize and diagnose it,
	...

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