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Finding Genius Podcast

Re-muscularizing the Heart—Dr. Charles E. Murray—Center for Cardiovascular Biology, University of Washington

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.41K Ratings

🗓️ 11 July 2019

⏱️ 45 minutes

🧾️ Download transcript

Summary

Heart failure is a disease that currently affects nearly five million people in the U.S., and it's also a disease that's defined by cellular deficiency. What does this mean? According to Dr. Charles E. Murray, professor of cardiovascular pathology at the University of Washington, this means that there's actually a pretty simple solution to the problem: all we need to do is figure out a way to replenish the deficiency and promote heart tissue regeneration, and this is exactly what he's working on in his lab. By differentiating stem cells into human cardiac muscle cells, Dr. Murray has discovered a way to create an endless supply of heart cells. When injected into injured or dead portions of the heart, the cells begin doing exactly what they should—dividing, connecting with existing heart cells, and eventually beating right along with them. Re-muscularization of the heart in this way provides great promise for those who have heart attacks or deal with any variety of heart disease. Dr. Murray explains in detail the physiology of the heart, how differentiated stem cells are assimilated into existing heart tissue, the tools that are allowing for unprecedented research and new findings in the field, the relationship between the microbiome and heart function, and so much more.

Tune in for all the details, and find a recent TED Talk on the topic at https://www.ted.com/talks/chuck_murry_can_we_regenerate_heart_muscle_with_stem_cells?utm_campaign=tedspread&utm_medium=referral&utm_source=tedcomshare.

Transcript

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0:00.0

You're listening to the Future Tech Podcast with Richard Jacobs.

0:09.0

Future Technologies such as Artificial Intelligence,

0:11.8

Stem Cells, 3D printing, gene editing,

0:14.6

Bitcoin, blockchain, the microbiome, quantum computing, virtual reality, and exploring space

0:21.0

are much closer than you might think.

0:23.0

In fact, many early versions of these technologies are in play right now,

0:27.0

and the companies that are using these technologies

0:30.0

to the focus of this podcast.

0:32.0

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0:34.4

podcasts. You may very well learn something that may change the course of your life

0:38.2

for the better, steer you towards a new career, or give you insight into

0:42.4

addressing a thorny medical problem.

0:44.6

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0:48.6

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0:53.0

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0:58.0

Thank you. Hello, this is Richard Jacobs. It would be Future Tech, and Future Tech Health

1:08.5

I have Dr. Charles Murray, Chuck Murray. Dr.

1:13.0

He's a cardiovascular pathologist.

1:15.0

Clinical interest span

1:16.8

ischemic heart disease, cardiac transplantation,

1:20.1

atherosclerosis, heart failure,

1:22.0

cardiomyopathy, valvular disease,

...

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