4.9 • 806 Ratings
🗓️ 18 May 2020
⏱️ 10 minutes
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0:00.0 | So up guys, Derek, more plates, more dates.com. |
0:02.0 | Today we're going to be talking about an update to the RAD 140 human trials. |
0:08.0 | So, you know, there's not, some of the hype has died down in the SARMs world around the clinical testing. |
0:15.5 | Some, you know, there's like the failed Austrian study. |
0:18.4 | LGD got, didn't get shelved, but it has sort of encountered, I guess, obstacles in terms of |
0:25.6 | getting, you know, phase three trials done in the States for the target, you know, therapeutic |
0:33.3 | intervention they were originally designing it for, which was hip fractures. |
0:38.0 | And then now, RAD 140 in particular, so this is something I've covered before, but it's |
0:44.2 | obviously worth updating because a lot of people following my channel obviously followed my |
0:48.9 | SARMs content. |
0:50.4 | And frankly, if you haven't seen any of my SARMs overviews, I without a doubt have the most comprehensive overviews of every single SARM on the entire internet. |
0:59.6 | Like there's nobody who has broken them down in the elaborate detail I have. |
1:02.7 | So I highly recommend if you haven't checked out my articles, which have all the citations in there, or the videos themselves, which are essentially just a video representation of what my written article is. |
1:15.0 | I highly recommend you check those out. But as far as RAD 140, so I had outlined before in my overview that in a preclinical study, RAD 140 significantly suppressed the growth and proliferation of breast cancer cells in vivo and in vitro |
1:30.2 | models of AR and ER, AR-R-endrogen receptor, and estrogen receptor-positive breast cancer. |
1:36.2 | RAD-140 has a promising preclinical profile and radius health. |
1:39.9 | They're the company who's developing it right now. |
1:41.9 | It's currently in the process of recruiting 40 postmenopausal |
1:45.2 | women with hormone receptor positive breast cancer into its first phase one clinical trial on |
1:49.9 | humans the main goal the study is to evaluate its safety profile tolerability pharmacokinetic |
1:54.7 | characteristics in hormone receptor positive breast cancer so you know one of the main criticisms of SARMs is that |
2:03.6 | the dosages using the studies are way lower than what people are using for performance |
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