Psychosis Blood Test, Altitude Genes, PCOS Cognition

Curiosity Weekly

Warner Bros. Discovery

Self-improvement, Science, Astronomy, Education

4.6 • 935 Ratings

🗓️ 14 March 2024

⏱️ 10 minutes

🔗️ Recording | iTunes | RSS

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Summary

Today, you’ll learn about a new blood test that can detect signs of psychosis and guide precision treatment, a gene mutation that happened in two different high altitude populations thousands of years apart, and new findings of the mental impacts of polycystic ovary syndrome.

Psychosis Blood Test

“Blood test predicts psychosis risk, most effective treatments.” UI School of Medicine. 2024.
“The Link Between Schizophrenia and Substance Use Disorder: A Unifying Hypothesis.” by Jibran Y. Khokhar, et al. 2019.
“Precision medicine for psychotic disorders: objective assessment, risk prediction, and pharmacogenomics.” by M.D. Hill, et all. 2024.

Altitude Genes

“Mutations in same gene allow two different groups of humans to thrive at extreme altitudes.” by Phie Jacobs. 2024.
“High-altitude living has changed more than just the genes of some Peruvians.” by Freda Kreier. 2020.
“How the people of the Andes evolved to live in high altitudes.” by Lizzie Wade. 2018.
“Mutations may reveal how Tibetans can live on world’s highest plateau.” by Michael Price. 2017.

PCOS Cognition

“Polycystic Ovary Syndrome Linked to Cognitive Decline in Midlife.” by Rhianna-lily Smith. 2024.
“Associations of Polycystic Ovary Syndrome With Indicators of Brain Health at Midlife in the CARDIA Cohort.” by Heather G. Huddleston, MD, et al. 2024.
“White Matter Microstructure and Cognitive Function in Young Women With Polycystic Ovary Syndrome.” by D. Aled Rees, et al. 2016.

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Transcript

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0:00.0	Hi, you're about to get smarter in just a few minutes with Curiosity Daily from Discovery.
0:09.0	Time flies when you're learning super cool stuff.
0:11.0	I'm Nate.
0:12.0	And I'm Callie. If you're dropping in for the first time
0:13.8	welcome to curiosity where we aim to blow your mind by helping you to grow your mind.
0:17.3	If you're a loyal listener, welcome back. Today you'll learn about a new blood
0:20.9	test that can detect signs of psychosis and guide precision treatment,
0:25.3	a gene mutation that happened in two different high-altitude populations thousands of years apart,
0:30.9	and new findings of the mental impacts of Polysistic
0:34.4	ovary syndrome. Without further ado, let's satisfy some curiosity.
0:38.0	Researchers at the Indiana University School of Medicine have made a breakthrough in the battle to
0:43.6	accurately diagnose schizophrenia. Oh wow we've talked a lot about psychotic
0:48.0	disorders like schizophrenia and I know they're notoriously hard to diagnose
0:52.0	accurately.
0:53.0	That's right.
0:54.0	And there's so much at stake because these disorders can absolutely derail everyday life.
0:59.0	By some estimates, schizophrenia itself affects over 3 million Americans, which is nearly one of every
1:03.9	hundred people and like I said it can be devastating. Right, hallucinations,
1:08.6	delusions, disorganized thinking I know those who suffer from it can have a hard time getting the right kind of help.
1:14.8	Sure and it's especially important to catch it early on and it's just so difficult to do.
1:19.6	All right so why is it so hard to diagnose early on?
1:23.0	Great question.
	...

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