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Science Quickly

Protein Test Could Complement Crime Scene DNA Analysis

Science Quickly

Scientific American

Science

4.41.4K Ratings

🗓️ 7 September 2016

⏱️ 2 minutes

🧾️ Download transcript

Summary

Researchers determined that the variation of a couple hundred proteins in a person's hair could be enough to single her out from one million individuals. Christopher Intagliata reports. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

This is a scientific American 60 second science. I'm Christopher Intagiyata.

0:07.0

DNA analysis is a staple of crime scenes and crime shows like HBO's The Night Of, or the old standby, CSI.

0:16.0

So we should get to get this a DNA lab, have them confirm it is our victim's blood,

0:22.0

and then, um then case closed.

0:25.0

And it's not just for crime.

0:27.0

DNA sequencing also helps determine our relationship to Neanderthals and our primate cousins.

0:32.0

Problem is, DNA is a relatively fragile molecule.

0:35.2

It doesn't last forever. What's more sturdy is protein. So now researchers have

0:39.8

come up with a way to use protein in a similar way to DNA, to link an individual to a piece of evidence or to determine ethnic background.

0:48.0

The protein source these scientists studied was human hair, from 76 individuals of European American, African American, and Kenyan descent.

0:57.0

And they determined that the variation of a couple hundred proteins in a person's hair could be enough to singular out from a group of 1 million individuals.

1:06.5

The way it works is that proteins are made according to instructions in DNA, so one individual's

1:11.7

genetic variations can result in slightly different proteins being made compared to another individual.

1:18.0

And by determining the protein composition, the scientists can then extrapolate info about the DNA. The results are in the journal

1:25.4

Ploss 1. The researchers say the technique still is not ready for prime time. Ideally the process

1:31.8

needs to be more sensitive to avoid

1:33.8

consuming valuable crime scene or archaeological samples in the analysis. And the

1:39.0

statistics behind the technique need to be validated too. But someday they say it could come within a

1:44.6

hair of DNA analysis. Thanks for listening. For Scientific American 60

1:51.9

Second Science, I'm Christopher and Daliata.

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