Protein Folding Problem
Let's Know Things
Colin Wright
4.8 • 593 Ratings
🗓️ 15 December 2020
⏱️ 26 minutes
🧾️ Download transcript
Summary
This week we talk about SETI@home, macromolecules, and AlphaFold2.
We also discuss proteins, Foldit, and CASP.
This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit letsknowthings.substack.com/subscribe
Transcript
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| 0:00.0 | SETI at Home, a moniker that contains the at symbol that you typically see in email addresses, in a manner that was a lot more |
| 0:23.7 | common in the late 90s and early 2000s, was initially released in mid-1999 as part of the larger |
| 0:31.5 | SETI program, SETI standing for the search for extraterrestrial intelligence. |
| 0:38.3 | This particular facet of that larger effort, which was set up to, among other things, |
| 0:44.3 | listened for signals from potential intelligent life forms, |
| 0:48.3 | living on other planets elsewhere in the universe, |
| 0:51.3 | took the shape of a distributed software platform, by the Berkeley SETI Research Center. |
| 0:58.0 | What that meant in practice was that you could download a piece of software onto your personal computer, |
| 1:04.0 | and that software would plug you in to the larger SETI research platform. |
| 1:09.0 | As long as you had at least an intermittent internet signal, |
| 1:12.5 | this software would send you chunks of data collected by mainly telescopes, like the recently |
| 1:18.6 | collapsed Erecibo telescope in Puerto Rico, and your computer, while not being used by you, |
| 1:25.0 | would donate its processing power to the larger undertaking of filtering that |
| 1:29.4 | telescope data for signals that could not be attributed to natural noise from the universal |
| 1:34.4 | environment or the technology used to collect those signals, the telescopes, the cables, |
| 1:40.9 | and so on. The sheer bulk of data that needed to be worked through in this way |
| 1:45.9 | justified the creation of this sort of project, because although it had a halfway decent budget, |
| 1:52.7 | as alien-related projects go, SETI's main bottleneck at this point was the ability to filter |
| 1:59.3 | and parse all the raw data it was collecting for meaning. |
| 2:03.6 | It was almost like it had collected countless haystacks, and that was great. |
| 2:07.6 | It was part of what they needed to do. |
| 2:09.6 | But in order to search those haystacks for needles, |
... |
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