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PBS News Hour - Segments

Promising new treatment for pancreatic cancer doubles survival rates

PBS News Hour - Segments

PBS NewsHour

News, Daily News

4.11K Ratings

🗓️ 1 June 2026

⏱️ 7 minutes

🧾️ Download transcript

Summary

A medical breakthrough in the fight against pancreatic cancer is showing promising results after decades of research. The experimental drug, taken once a day, extends patients' lives by slowing the progression of one of the deadliest cancers. Dr. Rachna Shroff, associate director of clinical investigations at the University of Arizona Comprehensive Cancer Center, joins Stephanie Sy for more. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

Transcript

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0:00.0

A medical breakthrough in the fight against pancreatic cancer is showing promising results after

0:05.4

decades of research. The experimental drug taken once a day extends patients' lives by slowing

0:11.2

the progression of one of the deadliest cancers. Stephanie Sy has more. Jeff, it's called

0:17.8

Deroxon RASIP. And put simply, it targets mutations of the KRAZ gene,

0:23.4

a common driver of pancreatic cancer that chem is viewed for a long time as undruggable.

0:30.1

Pancreatic cancer is expected to kill more than 52,000 Americans this year. It's often diagnosed

0:36.5

after it's already spread, putting the five-year

0:39.4

overall survival rate at a meager 13 percent. For most advanced patients, there's no cure. And standard

0:47.0

treatment has been chemotherapy. Experts say that could be about to change. For more on what this

0:53.6

means for patients and the future of

0:55.5

cancer treatment, I'm joined by Dr. Roshna Shroff, Associate Director of Clinical Investigations at

1:01.6

the University of Arizona Comprehensive Cancer Center. Dr. Shroff, this is hopeful to say the least.

1:08.9

And before we get into the details, I imagine you've treated and lost many pancreatic cancer patients over the years.

1:16.4

I lost my own mother to the disease very quickly a few years ago. What was your reaction when the results were read to the room over the weekend?

1:24.9

You know, I think, like you said, this was a monumental day in the treatment of

1:29.4

pancreatic cancer. I've been using the word game changer, and that is not a word that we use

1:34.3

lightly when it comes to treating this disease. And the honest truth is, it was tears,

1:40.6

tears of joy, you know, 16 years of treating this disease. And like you said, countless

1:45.1

lives lost to this horrible, horrible cancer. And so to see the results and to be in that room

1:53.0

with a number of people who have that same drive to kind of improve cancer outcomes for patients,

2:00.4

it was an incredibly emotional moment.

2:03.7

The studies participants were looking for a Hail Mary. They'd all undergone at least one round

...

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