Hello and welcome to the zero to finals podcast. My name is Tom and in this episode I'm going to be

going through the progestogen only injection. And you can find written notes on this topic at

zero to finals.com slash injection or in the contraception section of the zero definals obstetrics and gynecology book.

So let's get straight into it.

The progestogen-only injection is also known as depot, medroxyprogesterone acetate, or DMPA,

or simply the depot injection.

You'll see it listed as DMPA in the UK MEC guidelines.

It's given at 12 to 13 week intervals as an intramuscular or subcutaneous injection of

madroxy progesterone acetate, which is a type of progestin.

The DMPA is more than 99% effective with perfect use, but it's less effective with typical use

at 94%.

It's less effective with typical use because women may forget to book in for an injection

every 12 to 13 weeks.

It can take 12 months for fertility to return after stopping the injections, which makes it less

suitable for women who may wish to get pregnant in the near term.

There are two versions commonly used in the UK,

all of which contain madroxy progesterone acetate, the depotprovera, which is given as an intramuscular

injection, and cyanopress, which is a subcutaneous injection device that can be self-injected

by the patient.

Noristarats is an alternative to the DMPA that contains norathistorone and works for eight weeks.

This is usually used as a short-term interim contraception, for example after the partner has a vasectomy rather than a long-term

solution. Let's talk about the contraindications. The UK-MEC-4 contraindication is active breast

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