Hey all, welcome back to the Real Life Pharmacology podcast.

I am your host pharmacist, Eric Christensen.

Thank you so much for listening today.

As always, go sign up at real life pharmacology.com.

Get your free 31 page PDF on the top 200 drugs.

I pull in the most important clinical practice pearls,

as well as the things that are most likely to show up on your

pharmacology exams throughout school, as well as your board exams, if you're a nurse,

med student, or a pharmacy student. So go check that out, real-life pharmacology.com.

Simply an email will get you access to that for free. All right. So the drug of the day

today is Pramapexel. Brand name in this medication is Myrapex. This drug is a dopamine agonist. So mechanistically,

what that means, it binds dopamine receptors, and it stimulates them.

So it essentially has a similar effect to increasing the amount of dopamine in the brain.

The primary receptor, if you want to dig into the details a little bit, it's going to bind and agonize is D2,

but it also has effects on D3 and D4 as well.

Now, I want to re-educate you, remind you, the D2 receptor is often a primary target for antipsychotics,

which block dopamine and do the opposite of what Primapexol does, which is stimulate the effects of dopamine or stimulates these receptors.

So really, really important to remember that.

I have seen plenty of patients on both dopamine agonist medications as well as

dopamine blocking agents, and we're essentially opposing each other's effects there. And I'll

mention that again, of course, in the drug interaction section. But understanding that mechanism of

action, you should be able to understand that

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