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As a Woman

PMS, PMDD, & Your Brain | Dr. Sarah Hill

As a Woman

Natalie Crawford

Health & Fitness, Medicine

4.81.1K Ratings

🗓️ 10 February 2026

⏱️ 56 minutes

🧾️ Download transcript

Summary

Ever feel like a different person during your luteal phase? In this episode of the As a Woman podcast, board-certified fertility doctor Dr. Natalie Crawford sits down with award-winning researcher and psychologist Dr. Sarah Hill, author of the groundbreaking new book The Period Brain. They move beyond "bikini medicine" to explain how estrogen and progesterone literally rewire your brain's priorities, stress response, and social connections. If you’ve ever wondered why your mood, energy, or motivation shifts from one week to the next, or if you’ve struggled with Premenstrual Dysphoric Disorder (PMDD), this episode provides the science-backed roadmap you need to work with your hormones instead of against them. What You’ll Learn: - A deep dive into the "progesterone season" and how hormonal shifts change the way your amygdala processes relationship threats. They discuss why modern research has historically ignored the second half of the cycle and the importance of advocating for better data in women’s health. - Understanding the clinical difference between PMS and PMDD. They explore why some women are more sensitive to these fluctuations and who may be predisposed to sensitivities. - Why "one-size-fits-all" nutrition fails. Discover why your basal metabolic rate increases during the luteal phase and how to adjust your calorie intake to support your body’s increased energy needs and hormonal resilience. - The neurobiological differences between natural progesterone and synthetic progestins, and how each impacts mood, brain health, and well-being. - Tangible, approachable steps to support ovulation and increase cellular plasticity, including the role of morning sunlight, magnesium supplementation, and anti-inflammatory nutrition to help you work with your hormones instead of against them. Find Dr. Sarah Hill - Book: The Period Brain - Website: SarahEHill.com - Instagram: @SarahEHillPhD  Resources: Pre-Order The Fertility Formula ⁠https://www.nataliecrawfordmd.com/book⁠ Newsletter: nataliecrawfordmd.com/newsletter Instagram: @nataliecrawfordmd Youtube Channel: Natalie Crawford MD Interested in becoming a patient?: Fora Fertility Earn FREE CE/CME: Learn at Pinnacle App This episode is brought to you by The Pinnacle Podcast Network. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

I see, you know, a generation of women who don't know how to track their cycles, let alone know the follicular luteal phase.

0:05.0

The whole second half of the menstrual cycle is ignored and it's kind of mysterious. It's like our body and our brain are orienting themselves to prepare for the possibility of pregnancy. When you're a woman, you're a little bit of a moving target and to be able to move your treatment along with you. with you. Yeah, if you're cycling, we need to know that you're going to have different needs

0:23.0

at different times of your cycle. And and to be able to move your treatment along with you. Yeah, if you're cycling, we need to know that you're going to have different needs

0:22.9

at different times of your cycle, and you might have to advocate for yourself to get that care

0:27.6

to be different.

0:28.3

So many women I know have this narrative that their body is the enemy.

0:36.1

Welcome back to the As a Woman podcast.

0:38.2

I'm your host, Dr. Natalie Crawford, and today we are talking about something that affects

0:41.8

almost every woman, yet is still deeply misunderstood.

0:45.0

And this is how your menstrual cycle and your hormones impact your brain.

0:48.9

If you've ever wondered why your mood, energy, or motivation can shift from one week to the next,

0:53.4

or if you've ever wondered

0:54.7

if you struggle with PMS or PMDD. This episode's for you. Joining me today is Dr. Sarah Hill,

1:00.7

an award-winning researcher and psychologist, an author of the brand new book, The Period, Brain. Her work

1:06.1

dies into how our brains change across our cycle, why some women are more sensitive to hormonal

1:11.2

shifts than others, and what we can do about it all. In this episode, we're going to cover

1:16.4

what's really happening in the brain during PMS and PMDD, why some women experience severe

1:22.6

mood symptoms while others don't, and how to work with your hormones and not against them to protect your mental health and your well-being. If you've ever felt like your brain might be changing throughout your cycle, you're not imagining it. And this conversation is going to explain just why. Sarah, thank you so much for being here. I'm so excited to be here. I have been really waiting for this episode for a long time. I know it took a while to kind of

1:44.7

get you to town because you've been just so busy promoting your new book. Congratulations. Thank you.

1:49.5

What inspired you to write the period rank? You know, the whole second half of the menstrual cycle is

1:55.1

ignored and it's kind of mysterious. You know, there's all sorts of talk about estrogen and estrogen

1:59.9

does this and it makes you feel this and isn't it wonderful? And it's, you know, it's all sorts of talk about estrogen and estrogen does this and it makes you feel

...

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