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Unexplainable

Placebos work. Why?

Unexplainable

Vox

Science, Natural Sciences, Life Sciences

4.62.4K Ratings

🗓️ 6 November 2024

⏱️ 28 minutes

🧾️ Download transcript

Summary

For decades, scientists thought that placebos only worked if patients didn’t know they were taking them. Not anymore: You can give patients placebos, tell them they’re on sugar pills, and they still might feel better. No one is sure how this works, but it raises a question: Should doctors embrace placebos in mainstream medicine? (First published in 2021.) Guests: Ted Kaptchuk, professor at Harvard Medical School; Darwin Guevarra, professor of psychology at Miami University; Luana Colloca, professor at the University of Maryland School of Nursing For show transcripts, go to vox.com/unxtranscripts For more, go to vox.com/unexplainable And please email us! unexplainable@vox.com We read every email. Support Unexplainable by becoming a Vox Member today: vox.com/members Learn more about your ad choices. Visit podcastchoices.com/adchoices

Transcript

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0:00.0

It's unexplainable. I'm Noam Hassenfeld.

0:04.0

A couple weeks ago, we were talking about psychedelic treatments for mental health, like severe depression.

0:10.0

And there was this moment that really stuck with me.

0:13.0

This scientist put a bunch of patients under anesthesia.

0:17.0

He gave some of them ketamine, and he gave others a placebo.

0:26.1

But their symptoms got better across the board, even in the ones who didn't get the drug.

0:30.8

It seemed like it wasn't necessarily the drug that was making these patients feel better,

0:34.8

as much as it was their brains, their expectations.

0:40.5

So this week, we wanted to share an episode that really dives into this exact idea,

0:46.9

how placebos and really people's brains are way more powerful than we might think.

0:50.0

It was reported by our former editor, Brian Resnick,

0:53.2

and it's an episode I still think about all the time.

0:55.4

So I'm really excited to share it with you this week.

0:57.3

Okay, here's Brian.

1:02.2

I want you to imagine this.

1:04.7

Let's say you go to the doctor's office and you have this huge headache.

1:06.7

You're just complaining, you're nauseous.

1:08.4

It's just nothing's going right for you.

1:10.7

And the doctor, she gives you a prescription for sugar pills, like,

1:15.3

placebo's, and tells you to take them.

1:17.7

Okay.

1:18.3

How would you feel?

...

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