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Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Phentermine Pharmacology Podcast

Real Life Pharmacology - Pharmacology Education for Health Care Professionals

Eric Christianson, PharmD; Pharmacology Expert and Clinical Pharmacist

Education, Health & Fitness, Medicine

5716 Ratings

🗓️ 29 September 2022

⏱️ 12 minutes

🧾️ Download transcript

Summary

In this podcast episode, I break down the pharmacology, adverse effects, pharmacokinetics, and drug interactions of phentermine.



Phentermine has some CNS stimulant activity so adverse effects like insomnia, hypertension, and tachycardia are possible.



Pay attention to drugs that can oppose the effects of phentermine and cause weight gain such as mirtazapine and sulfonylureas.



Phentermine is a controlled substance so the risk of addiction and dependence is possible.

Transcript

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0:00.0

Hey, all, welcome back to the Real Life Pharmacology podcast. I'm your host pharmacist, Derek Christensen.

0:06.1

Thank you so much for listening today. As always, go to Real Life Pharmacology.com. Get your free 31-page

0:13.7

PDF on the top 200 drugs. It's a great little study guide, great review if you're out in practice

0:20.1

or going through pharmacology exams or board exams.

0:23.5

You'll definitely enjoy that resource.

0:26.1

All it'll cost you is an email.

0:28.1

Subscribe to our list.

0:28.9

We've also got updates as to when we've got new content and other things available as well.

0:35.1

All right.

0:35.9

The drug of the day today is phentermine. Brand name of this medication is

0:41.0

Atepex, also called FASTin at times as well. So this drug is classified as a central nervous

0:51.7

system or CNS stimulant.

0:55.0

The use of this medication in clinical practice,

0:59.2

I only see it used from one thing and one thing alone,

1:02.6

and that's weight loss or weight management.

1:05.5

Okay, so being a CNS stimulant,

1:09.3

you could understand that it can reduce appetite.

1:13.3

And it primarily does this by increasing release of norapinephrine and possibly dopamine as well.

1:21.8

So its pharmacology really kind of follows along the lines of amphetamine and amphetamine derivatives.

1:29.4

So knowing that, you can recognize some of the adverse effects that you might encounter there as well.

1:36.0

So a couple things about weight loss or weight management that I wanted to mention.

1:42.6

In practice, I'm generally seeing less of this medication

...

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