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NutritionFacts.org Video Podcast

Pesticide Exposure and Hypospadias Birth Defects in Vegetarians

NutritionFacts.org Video Podcast

Michael Greger, M.D. FACLM

Nutrition, Alternative Health, Health & Fitness

4.8951 Ratings

🗓️ 21 May 2025

⏱️ 4 minutes

🧾️ Download transcript

Summary

What role do vegetarian diets and organic foods play in the prevention or promotion of a birth defect called hypospadias?

Transcript

Click on a timestamp to play from that location

0:00.0

I'm excited to introduce Dr. Christine Dennis, our new senior research scientist,

0:08.0

who has been researching and scripting new video topics and, as you're here today, narrating some as well.

0:14.0

In this video, Christine delves into the association between vegetarian diets and hypospatious birth defects to see if it holds

0:23.6

up in the light of new research.

0:29.6

In 2000, a study found that a vegetarian diet during pregnancy was associated with hypospadias,

0:39.5

a specific birth defect of the penis.

0:42.2

The author suggested that it may be due to the greater exposure to phytoestrogens, which are found in soy foods.

0:48.5

But if you look globally, while there is an extraordinarily high prevalence in North America and Europe,

0:55.4

it's extremely low in a country like Japan, which has the highest per capita soy intake in the world.

1:01.9

In fact, in Japan, a low maternal intake of soy phytoestrogens has been associated with

1:07.1

elevated risk of hypospatias. So if anything, soy may be protective. If soy foods aren't

1:14.6

the hormone disruptors, what in a vegetarian diet might be? Well, occupational exposure to pesticides

1:20.5

is associated with higher risk. So might low-level pesticide exposure among those eating more

1:26.7

fruits and vegetables, like vegetarians,

1:29.2

help explain it?

1:31.4

If you randomize people to a more plant-based Mediterranean diet, you see a large increase

1:36.4

in the amount of pesticides flowing through their body.

1:39.3

Though, of course, if you put them on a Mediterranean diet with organic fruits and vegetables,

1:43.8

you see a 90% drop in

1:45.8

pesticide exposure. So does organic food consumption during pregnancy reduce hypospatius risk? Apparently so,

1:55.0

cutting the odds about in half, particularly when it comes to choosing organic vegetables and dairy.

2:00.9

Though the only other study to look at organic food choices and hypospadias

...

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