4.9 • 806 Ratings
🗓️ 8 October 2021
⏱️ 7 minutes
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0:00.0 | You're talking about IGF1 and growth hormone. |
0:04.4 | I think it, I'm curious to your thoughts on, you know, on peptides, you know. |
0:08.9 | So right now there's a huge surge in the number of people that are interested in peptides |
0:14.3 | because it sounds not as perhaps scary to them as it does hormone augmentation. |
0:19.2 | Again, and I, I really, you know, |
0:22.9 | I don't think that people should run out and start tinkering with their endocrinology. I mean, |
0:26.9 | you need to work with a physician if you're going to do that at all. And ideally it's because |
0:30.6 | there's a real clinical need. But peptides are interesting because there are a couple |
0:34.4 | issues that come to mind. One is, so I've seen examples of |
0:39.7 | people who take things like sermoralin, test some more and Ipermoralin in order to get some |
0:44.7 | more growth hormone release in sleep and end up with doubling or even tripling of their |
0:50.3 | prostate specific antigen. Have you heard about this? Is that the sap? |
0:55.0 | Yeah, I heard it from you specifically, and I remember I probably wrote it on like a topic |
0:59.7 | list to dive into more, but I don't know what would cause that specifically, although I do |
1:05.8 | know the function by which a lot of these peptides work is through agonism of the |
1:09.4 | grelin receptor, which has |
1:11.5 | interactions, significant interactions with stress as well. So it's not just about, I think a lot of |
1:16.7 | people, they think you take this peptide and all of a sudden your pituitary just like spits out |
1:20.9 | more GH or something. But in reality, it's stimulating a receptor that is designed to make you hungry. |
1:29.7 | And in rodents, it's actually something they chronically agonized to induce PTSD, which is like kind of sketchy when you think |
1:35.4 | about, I'm not saying you shouldn't use peptides, by the way, but in general, like some of them, |
1:39.2 | like the, the ones that are more chronic around the clock and aren't like pulsatile in nature, |
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