Today we're going to be talking about statins and the possible adverse

reaction of my algae and why it's so important to know about this adverse

reaction is because statins are going to be given all the time, especially

used in the primary and secondary prevention of coronary disease. Now stans are also

going to be the only lipid-lowering medication that has proven reduction in the patient's mortality.

They work by inhibiting H.M. G. Koei to mevallonic acid.

Now the reason or the thought as to why muscular injury occurs are really

going to be three schools of thoughts here. This one is going to be the

reduction or the inhibition of the synthesis of coq10, decreased mitochondrial function, and finally,

altered muscle protein degradation.

Now, these are the three theories as to why muscular injury occurs, but again, it's not really

known as to why this exactly occurs.

All right, now let's go over a few definitions here.

Now my ALJIA means that we have muscular discomfort with or soon after

exercise so we're going to have soreness, cramping, things of that nature and we normally or we should

have a normal

c-K level. Myopathy means we have muscular weakness

with or without increased c-K levels. Myocitis

means muscle inflammation. Myoncrosis means we have an elevation in

c. K levels and there's going to be varying degrees here.

Mild is going to be when we have a 3 to 10X elevation of CK.

Moderate is when we have 10 to 50 times elevation.

...