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The Journal.

Ozempic Is a Hit. So Why Is the Drugmaker’s CEO Out?

The Journal.

The Wall Street Journal

Daily News, Business News, News

4.25.3K Ratings

🗓️ 21 May 2025

⏱️ 17 minutes

🧾️ Download transcript

Summary

Blockbuster drugs. Rising profits. Strong sales. And yet, Novo Nordisk, the Danish company behind the GLP-1 drugs Ozempic and Wegovy, made a surprising move last week: It pushed out its CEO. WSJ's Peter Loftus charts the rise of Ozempic and the fall of CEO Lars Jorgensen. Jessica Mendoza hosts.  Further Listening: Trillion Dollar Shot  Why WeightWatchers Wants in on Drugs Like Ozempic   Sign up for WSJ’s free What’s News newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

In the world of Big Pharma, this is the sound of liquid gold.

0:14.9

An assembly line in Denmark fills glass vials with somaglite.

0:19.0

It's the active ingredient in the injectable drug

0:21.2

that's become a bona fide

0:22.5

cultural phenomenon.

0:28.3

Where would you say

0:32.6

Ozempic ranks

0:33.7

in terms of successful drugs that you've covered?

0:36.7

One of the most successful of all time.

0:40.6

It's up there from a financial perspective, but also just from a cultural impact perspective.

0:45.8

Right.

0:46.1

It's one of the biggest deals. That's rare.

0:48.9

Tell me about the company behind this blockbuster drug.

0:52.5

Well, a company is Novo Nordisk, which is based in Denmark,

0:56.0

and they've been around for about 100 years.

0:59.0

Most of that time, probably a lot of Americans never heard of it.

1:03.0

Over the last decade, our colleague Pete Loftus has watched

1:07.0

Novo Nordisk grow into a pharmaceutical juggernaut.

1:10.0

Novo is one of the a pharmaceutical juggernaut.

1:14.6

Novo is one of the most valuable companies in Europe by stock market capitalization,

1:19.0

thanks to the spectacular success of OZempic and its sister drug Wagovi.

1:26.5

Last year, their combined sales of just those two drugs were over $26 billion.

...

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