4.9 β’ 806 Ratings
ποΈ 28 March 2016
β±οΈ 26 minutes
ποΈ Recording | iTunes | RSS
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0:00.0 | So, guys, Derek, more plates, more dates.com. Today we're going to be talking about |
0:05.7 | Osterine, also known as MK2866 and Inobosar. So we're going to be going over everything |
0:13.2 | there is to know about it, complete overview, top to bottom. Osterine is the most well known and |
0:19.6 | extensively studied selective endogen receptor modulator right now. |
0:23.8 | It's categorized as a SARM because of its unique selectivity at the androgen receptor where it exhibits a significant amount of |
0:31.4 | anabolic activity in the body relative to endogenic activity. |
0:36.0 | So it's being researched to determine if it's a potential treatment for the management |
0:41.4 | of muscle and bone wasting diseases. |
0:43.5 | Basically, I'm going to talk somewhat briefly. |
0:47.0 | It's going to be pretty elaborate, actually, about its potential therapeutic applications, |
0:51.9 | side effects, anecdotal findings based on my own personal research, |
0:56.0 | et cetera. So what is it exactly? It's also known as the Nobosarm, GTX-024, and MK2866. So |
1:06.7 | SARM and SARMs like Austerine stimulate androgen receptors in a selective way, |
1:12.5 | whereby they induce a significantly greater amount of anabolic activity in the body |
1:17.8 | relative to the endogenic activity. |
1:20.7 | So that's sort of where, you know, you define something as a SARM as its selective action |
1:26.1 | at the endergen receptor and the way it activates it and you know induces and |
1:30.7 | transcribes its effects. Testosterone was just to give it a bit of |
1:34.9 | background on you know the conception of SARMs. Testosterone was the first |
1:38.8 | anabolic androgen to be approved for use in a clinical setting. However, |
1:43.8 | its scope of versatility has always been |
1:46.2 | severely limited by its endrogenicity and its pharmacokinetic issues. So most notable being its |
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