Organoids: Regrowing Tumors Before Treating Them—Senthil K. Muthuswamy— Muthuswamy Lab

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.4 • 1K Ratings

🗓️ 13 December 2019

⏱️ 28 minutes

🔗️ Recording | iTunes | RSS

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Summary

Associate Professor at Harvard Medical School, Director of Cell Biology at the Cancer Center at Beth Israel Deaconess Medical Center, and Principal Investigator at Muthuswamy Lab, Senthil K. Muthuswamy, Ph.D. is working to better understand the molecular biology of cancer and the most effective method of treating it by creating organoids from patient tumors. When cultured under the proper conditions, a sample of tissue from a patient's tumor will grow into a 3D structure that resembles the patient's tumor.

Once that's been accomplished, the organoid can be used to determine which drugs will most effectively treat the specific tumor at hand. This approach addresses one of the main challenges to chemotherapy and targeted therapy, which is that not all patients will respond to the same drug in the same way—even if they have the same type of cancer. Dr. Muthuswamy's lab is currently working with breast and pancreatic tumors.

On today's episode, you will learn:

Why two people with a certain type of cancer respond differently to the same treatment
What types of research are being done with the use of organoids
What the next five years will bring for Dr. Muthuswamy's lab and organoid-based drug and immunotherapy research

Transcript

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0:00.0	You're listening to the Future Tech Podcast with Richard Jacobs.
0:09.0	Future Technologies such as Artificial Intelligence,
0:11.8	Stem Cells, 3D printing, gene editing,
0:14.6	Bitcoin, blockchain, the microbiome, quantum computing, virtual reality, and exploring space
0:21.0	are much closer than you might think.
0:23.0	In fact, many early versions of these technologies are in play right now,
0:27.0	and the companies that are using these technologies
0:30.0	for the focus of this podcast.
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0:34.4	podcasts. You may very well learn something that may change the course of your life
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0:42.4	addressing a thorny medical problem.
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0:58.0	Thank you. Hello this is Richard Jacobs with the Future Tech and Future Tech health
1:09.0	podcast. Today's guest is Santill Musso Swami. He's a principal investigator at a lab named after him.
1:16.4	He is a director of the Cell Biology Program Cancer Center, co-chief division of
1:21.2	translational research and technology Innovation, Associate Professor, Department of Medicine and
1:26.6	Pethology at the Beth Israel Deaconess Medical Center at Harvard Medical School in Boston, Massachusetts.
1:33.2	We're going to have a great discussion today.
1:36.0	Cynthia has been working to help people that are facing cancer
	...

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