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The Oprah Podcast

Oprah and Dr. Ania Jastreboff on How People Treat You Differently After Weight Loss

The Oprah Podcast

Harpo

Society & Culture

4.6711 Ratings

🗓️ 21 January 2025

⏱️ 54 minutes

🧾️ Download transcript

Summary

In this episode of The Oprah Podcast, Oprah continues her conversation with Dr. Ania Jastreboff, an endocrinologist and associate professor at the Yale School of Medicine, about the anti-obesity GLP-1 medications that are changing the world of weight loss. Oprah and Dr. Ania talk about what happens to a person’s mental health, body image and how the world treats them after losing a significant amount of weight. Joined by clinical psychologist Dr. Rachel Goldman, assistant professor at NYU Grossman School of Medicine, Oprah and Dr. Ania speak to people using the GLP-1 medications like long-time Harpo producer, Brian Piotrowicz, who reveals how people treat him differently now that he’s lost a significant amount of weight in a short period of time. Several other guests from across the country also share how their lives have changed after GLP-1 weight loss including a woman who lost over 160 pounds. Finally, we will get an update from several guests that appeared on the ABC Oprah Special: Shame, Blame and the Weight Loss Revolution including high school student Maggie who lost over 100 pounds. For more information on Dr. Rachel Goldman Follow Dr. Rachel on Instagram Follow Michaela on TikTok Follow Michaela on Instagram Follow Anna on Instagram Follow Jewell on TikTok Follow Jewell on Instagram Follow Jewell on YouTube Follow Marissa on Instagram Follow Marissa on TikTok Follow Oprah’s Producer Brian on Instagram Watch Part 1 Here. SUPPORT THE SHOW Subscribe: https://www.youtube.com/@Oprah Follow Oprah Winfrey on Social: Instagram Facebook TikTok Listen to the full podcast: Spotify Apple Podcasts #oprahsbookclub Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

Hi again, everybody, and thank you for listening to the Oprah podcast. And hello to everybody who's

0:06.3

watching us on YouTube. In the few years since GLP1 medications were approved by the FDA for use for obesity,

0:14.2

we have seen how these drugs can result in dramatic weight loss. But when you lose up to 100 pounds or even more,

0:21.7

how does that impact the self-image you had for most of your life?

0:26.1

I wish I could say, oh, my gosh, it's just been the most perfect experience ever.

0:30.6

Do people treat you differently?

0:32.3

People look me in the eyes now, and everyone was so much friendlier to me.

0:35.8

How do you see yourself in the world?

0:37.6

My life opportunities have opened up, but it's not without its complications.

0:42.2

On this episode of the Oprah podcast, my conversation continues with Dr. Anya Yastrobaugh,

0:48.1

an endocrinologist and associate professor at the Yale School of Medicine, and we're going to be

0:52.8

joined by licensed psychologist Dr. Rachel Goldman. For this episode, our guests asked us to share their before and after

1:00.3

weight loss pictures because they believe the photos are an important part of their journey.

1:07.8

Welcome to part two of our conversation about weight loss medications. I'm so glad we get another

1:13.8

chance to open up the subject for people who are still confused. I'm here with Dr. Anya Yastrobov,

1:21.0

who is an endocrinologist and an associate professor at the Yale School of Medicine. And I wanted to

1:27.2

introduce you to one of my

1:28.3

producers, longtime producers, Brian. So Brian, tell us why you started GLP-1s. I've seen the transformation,

1:36.7

but when I first started talking about it a year ago, you seemed reluctant. You were like,

1:41.9

I'm going to wait and see, I'm going to think. And I, you know,

1:45.4

have my own burdens to carry and want people to do whatever is good for them. And so I stopped right

1:51.6

there when I realized that you were not ready and wasn't my business to tell you what to do.

...

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