A Replacement Heart, From A Pig

This week, doctors reported that they had successfully transplanted a heart taken from a pig into a human being, a type of procedure known as xenotransplantation. The pig had been genetically modified to lack a certain protein thought to be responsible for organ rejection in previous transplant attempts.

The patient, a 57 year-old man, will be monitored for any sign of rejection or infection with a porcine virus—but doctors are hopeful that the work will lead to further transplants and a new source of replacement organs for people.

Science journalist Roxxane Kamsi joins Ira to talk about that and other stories from the week in science, including research into how antivirals work in people infected with HIV, the role of clothes dryers on microplastics pollution, a push to make the U.S. electric grid greener, and more.

Omicron Sparks Surge In Pediatric Hospitalizations

Omicron’s rapid spread has many parents and caregivers of young children on edge. The most recent CDC data shows 5.3 cases per 100,000 children under four are hospitalized with COVID-19 in the United States, the highest number since the pandemic started. And kids under five still aren’t eligible to be vaccinated.

When word went out that we were going to answer questions about COVID and kids, we were flooded with questions from our listeners.

To help answer some of those questions, and better understand how to keep our kids safe, Ira spoke with Dr. Yvonne Maldonado, pediatrician, and professor of global health and infectious diseases at Stanford University, and Dr. Rick Malley, infectious diseases specialist at Boston Children’s Hospital and professor of pediatrics at Harvard Medical School.

Ivermectin’s False Reputation Exemplifies How Misinformation Spread

Not a single scientific or health authority in the U.S. recommends the use of the anti-parasitic drug ivermectin to treat or prevent COVID-19. Still, some Americans see the unproven drug as a way out of the pandemic.

Ivermectin is mostly used in large animals and is approved by the U.S. Food and Drug Administration for treating human conditions, including head lice and stomach worms. But across the country, demand for the drug has surged in recent months — leading to a spike in hospitalizations for human exposures to ivermectin.

The drug is among the latest politically divisive public health issues unfolding across the country. The situation has fast-tracked conversations about the risks and benefits of publicizing research findings that have not yet been vetted by the scientific community. That’s because much of the misinformation on ivermectin draws on insufficient data — some coming from low-quality studies, including ones that were retracted after further examination revealed problems and even potential fraud.

Read the rest at sciencefriday.com.

A Massive New Find Of Icefish Found Near Antarctic

The frigid waters near Antarctica are home to an unusual family of fishes collectively known as the icefish. They have translucent blood, white hearts, and have adapted to live without red blood cells or hemoglobin, relying instead on copper compounds that function better at low temperatures. Now, researchers mapping the floor of the Weddell Sea report in the journal Current Biology that they have spotted a massive colony of the unusual sea creatures—containing over 60 million icefish nests.

“A few dozen nests have been observed elsewhere in the Antarctic, but this find is orders of magnitude larger,” said Autun Purser, of the Alfred Wegener Institute in Bremerhaven, Germany. Purser and his colleagues were mapping the seafloor of the Filchner ice shelf region, in an area of thermal upwelling, where there are slightly warmer temperatures. They found masses of icefish nests clumped close together as far as the eye can see, somewhat like a land-based colony of nesting penguins.

Purser joins Ira to talk about the discovery, and what’s known about the ultra-cold ecosystems of Antarctic seas.