Oct 29, 2021 This Week in Cardiology

This Week in Cardiology

Medscape Podcasts

Medicine, Science, Health & Fitness

4.9 • 963 Ratings

🗓️ 29 October 2021

⏱️ 21 minutes

🔗️ Recording | iTunes | RSS

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Summary

ESUS, CAC 0, Takotsubo syndrome, and chest pain are the topics John Mandrola, MD, covers in today's podcast. To read a partial transcript or to comment, visit:

https://www.medscape.com/twic

I – ESUS

Anticoagulation May Benefit Stroke Patients With LV Dysfunction https://www.medscape.com/viewarticle/961815

- Left Ventricular Dysfunction Among Patients With Embolic Stroke of Undetermined Source and the Effect of Rivaroxaban vs AspirinA Subgroup Analysis of the NAVIGATE ESUS Randomized Clinical Trial

https://jamanetwork.com/journals/jamaneurology/article-abstract/2785030

- Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source

https://www.nejm.org/doi/10.1056/NEJMoa1802686

- Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source

https://www.nejm.org/doi/10.1056/NEJMoa1813959

II – CAC

CAC Score 0 Unreliable to Rule Out Stenosis in Younger Patients https://www.medscape.com/viewarticle/961801

- Association of Age With the Diagnostic Value of Coronary Artery Calcium Score for Ruling Out Coronary Stenosis in Symptomatic Patients https://jamanetwork.com/journals/jamacardiology/fullarticle/2785586

- The Case Against Coronary Artery Calcium Scoring for Cardiovascular Disease Risk Assessment

https://www.aafp.org/afp/2019/1215/p734.html

III – Takotsubo Cardiomyopathy

Broken Heart Syndrome: On the Rise, Especially in Women 50-74

https://www.medscape.com/viewarticle/961307

- Sex‐ and Age‐Based Temporal Trends in Takotsubo Syndrome Incidence in the United States

https://www.ahajournals.org/doi/10.1161/JAHA.120.019583

IV- Chest Pain Guidelines

AHA/ACC Issues First Comprehensive Guidance on Chest Pain

https://www.medscape.com/viewarticle/961806

- 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines https://www.jacc.org/doi/10.1016/j.jacc.2021.07.052

Transcript

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0:00.0	You're listening to this week in cardiology from the heart.org on medscape.
0:09.7	You can now access the latest in medical news on your Amazon Alexa enabled device.
0:14.3	Join me, Perry Wilson, every weekday morning for Medscape Medical Minute, where I highlight
0:18.8	the top medical stories of the day.
0:21.1	To add Medscape Medical Minute to your flash briefing, search for Medscape
0:24.4	Medical Minute on Amazon and click enable. Or open the Amazon Alexa app, go to
0:29.0	skills, search for Medscape Medical Minute and click enable. Then say,
0:33.4	Alexa, what's the news or Alexa, what's my flash briefing? I hope you'll join us.
0:38.6	Hi everyone, this is John Mandrola from the Heart.org Medscape Cardiology, and this is
0:46.1	this week in Cardiology for October 29, 2021.
0:50.7	This week, stroke of unknown source, coronary artery calcium, Tachacubo syndrome, and chest pain.
1:00.0	First a brief note on COVID in the United States cases hospitalizations and deaths continue to decline thank goodness
1:08.8	The first topic is anti coagulation in post stroke patients with left ventricular dysfunction.
1:15.0	Now how best to treat a patient with a stroke of unknown source comes up often
1:20.0	especially for us EP docs who are often asked to place implantable loop
1:24.7	recorders to monitor for AFIB after stroke. The journal Jama Neurology has
1:31.1	published an interesting post hoc analysis of the Navigate
1:35.1	ESIS trial of Riveroxiband versus aspirin in patients who have had a
1:40.0	symbolic stroke of unknown source. The question for this specific analysis was
1:45.4	whether left ventricular systolic dysfunction modified the effect of
1:50.3	Riveroxibaban versus aspirin.
1:53.6	In other words, was their heterogeneity of treatment effect?
	...

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