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The Dr. Hyman Show

Obesity Isn’t Your Fault: Biology, Addiction & Solutions with Dr. David Kessler

The Dr. Hyman Show

Dr. Mark Hyman

Health & Fitness, Nutrition, Medicine

4.68.7K Ratings

🗓️ 1 October 2025

⏱️ 76 minutes

🧾️ Download transcript

Summary

Obesity is often seen as a matter of willpower, but science tells a different story. My guest today, Dr. David Kessler—former FDA commissioner, lawyer, physician, and the man who took on Big Tobacco—explains why biology, not blame, drives our struggles with weight. On this episode of The Dr. Hyman Show, we talk about why weight struggles are so common today, what new drugs can and can’t do, and how his new FDA petition targets one of the biggest culprits: processed refined carbs. Catch the full conversation on YouTube, or listen wherever you get your podcasts. [YOUTUBE THUMBNAIL] You’ll learn: • How food companies use ingredients like processed refined carbs to make products irresistible • Why GLP-1 drugs help many lose weight—but can’t fix the food environment driving the crisis • How belly fat fuels heart disease, diabetes, and cancer—and why ultraprocessed foods are a big part of the problem • Simple ways to break free from foods engineered to make you overeat • What Dr. Kessler’s FDA petition could mean for limiting processed carbs in our food supply and improving our collective health Plus, here’s a bonus: We’ve adapted Dr. Kelsser’s petition into a free PDF guide—The Hard Truth About Processed Carbs—so you can see exactly how these ingredients affect your health…and why his FDA petition REALLY matters. Tune in, download the guide, and find out how you can be part of the solution. View Show Notes From This Episode Get Free Weekly Health Tips from Dr. Hyman https://drhyman.com/pages/picks?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Sign Up for Dr. Hyman’s Weekly Longevity Journal https://drhyman.com/pages/longevity?utm_campaign=shownotes&utm_medium=banner&utm_source=podcast Join the 10-Day Detox to Reset Your Health https://drhyman.com/pages/10-day-detox Join the Hyman Hive for Expert Support and Real Results https://drhyman.com/pages/hyman-hive This episode is brought to you by Seed, Paleovalley, Function Health, Timeline and AirDoctor. Visit seed.com/hyman and use code 25HYMAN for 25% off your first month of Seed's DS-01® Daily Synbiotic. Get nutrient-dense, whole foods. Head to paleovalley.com/hyman for 15% off your first purchase. Join today at FunctionHealth.com/Mark and use code HYMAN100 to get $100 toward your membership. Support essential mitochondrial health and save 20% on Mitopure. Visit timeline.com/drhyman to get 20% off today. Get cleaner air. Right now, you can get up to $300 off at airdoctorpro.com/drhyman.

Transcript

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0:00.0

I ran the FDA, and here I can't control my weight. So I ended up after COVID, 40 pounds heavier. And I didn't like myself. I said, look, I got to understand why do I keep on gaining this path? And what is it the root of this problem? Twenty-five percent of us are going to develop heart failure. Half of us are pre-diabetic. 25 percent of us are going to have stroke. We're going to talk about why we're in a metabolic crisis in America,

0:21.6

why our food system is so messed up,

0:23.4

and what we can do about it both from the personal and the policy perspective. David Kessler is a physician, an author, a public health leader, who has served as chief science officer of the White House COVID-19 response team, and previously as the commissioner of the FDA. He's a pediatrician by training. He also served as the dean of the medical schools at Yale and the University of California, San Francisco. It's not your fault, you're fat, because the food industry wants to blame you. And that is as far from the biological truth as you could possibly get. I think it's important to change our paradigm of how we think about addiction. I filed this petition with HHS. I think

0:55.1

FDA has no choice. It's going to have to get its act together and say, how do we change this

1:00.0

food environment? They're going to throw hundreds of millions of dollars of legal arguments against

1:04.0

this. So how strong do you think this would hold up in court? As you know, I'm always talking about how central the gut is to living a long healthy life.

1:17.6

A high-quality probiotic is one of the most important things you can do for your gut, which

1:21.4

is why I have been recommending seeds DSO-1 daily symbiotic.

1:24.9

I've reviewed hundreds of probiotics over the years, but DSO-1 is the one I

1:28.6

personally trust and take every day. Seeds DSO-1 combines 24 probiotic strains with a pomegranate-based

1:35.3

prebiotic for benefits well beyond digestion, easing bloating, supporting immune function,

1:40.1

strengthening the gut barrier, promoting clear, glowing skin, and even reducing visible signs of aging.

1:45.4

Its patented capsule and capsule design ensures these probiotics actually make it to the colon alive

1:50.2

where they have the most impact. That's why I join Seed's clinical board and why I recommend

1:54.5

DSO1 as part of any daily routine. Seed is offering my listeners 25% off your first month. Just head to seed.com slash hymen and use the code 25 hymen. Did you know most so-called health bars today have as much sugar as a candy bar? Most are made with refined sugar, artificial sweeteners, low-quality protein, and other ingredients that can spike your blood sugar, cause bloating, and deliver very little nutritional value. That's why I recommend Paleo Valley's superfood bars. They're made with eight plus organic superfoods and

2:22.0

grass-fed bone broth protein which supports your gut, joints, and skin while giving you

2:26.4

clean, sustained energy. These bars are nutrient dense, protein rich, and completely free

2:31.0

from junk, a snack you can actually feel good about. They come in four delicious year-round flavors, dark chocolate chip, apple cinnamon, lemon meringue, and red velvet cake. And right now, their pumpkin spice superfood bar is back for a limited time. It's seasonal, delicious, and packed with clean ingredients. I keep these bars on hand for myself and recommend them to my patience. They're perfect for when hunger strikes and you need a snack that fuels your body, not spikes it. Head to paleovali.com slash hymen for 15% off your first purchase and try them today. David, welcome to the Dr. Hyman Show. It's so good to have you here in person. We did a show before, which everybody should listen to about one of your previous books. But we're going to talk about diet, drugs, and dopamine, the new science of achieving a healthy weight. But it's really way more we're going to talk about, which is why we're in a metabolic crisis in America, why our food system is so messed up, and what we can do about it, both from the personal and the policy perspective, because you,

3:25.1

for those of that you don't know, you have a very storied career. You were the FDA commission

3:30.4

a Democrat and a Republican president, Clinton and Bush, and you have also got a law

3:37.0

degree from the University of Chicago. So you've got this really interesting kind of

3:40.3

juxtaposition of medicine and law. It's allowed you to take on some really big issues. And you were the

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