When you think of nicotine, you probably think about smoking, chewing tobacco,

with the addictive potential of nicotine. But in today's session, we're going to talk more about

the favorable effects of nicotine and its association with acetylcholine neurotransmittersynthesis,

which impacts learning, memory, and movement. And as such, acetylcholine and nicotinic acid,

acetylcholine receptor augmentation and dysfunction is linked with Alzheimer's, schizophrenia,

attention deficit disorder, myastenia gravis, and as well as autism and a whole host of other

conditions. So as a nicotine user myself, no, I don't smoke, no, I don't use zins, no, I don't

use chewing tobacco. I use a product called NICNAC Naturals, and I'll link it below. Not all the time,

I'm not addicted to it, but there are certain applications, and I think therapeutic timing

when it comes to nicotine use that I want to bring to your attention and highlight some of the

recently published academic literature and talk about use cases for this specifically around

learning, memory, cognition, focus, and also movement. So let's talk a little bit more also

about the inflammatory process and a inflammatory reflex arc known as the colonurgic anti-inflammatory

reflex arc that is actually augmented by nicotine and choline. And I think this is another use case,

and because it doesn't fit in nicely with Alzheimer's and schizophrenia and cognition,

I wanted to just share this with you right up front because when it comes to nicotine and its

potential therapeutic uses, I really don't believe many people understand this powerfully important

anti-inflammatory reflex arc known as the colonurgic anti-inflammatory pathway. And so as you

can see on this image here, this is figure nine, I don't share the reference in the show notes,

but what you see here is how acetylcholine impacts the vagal nerve. We hear all about the vagal nerve

when it comes to improving digestion, gastrointestinal motility in this process of peristaltus and the

movement of the bowels, which anecdotally I think is a nice use case scenario when it comes to nicotine.

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