New Rapid Fat Loss Study, Menopause Weight Loss Resistance & More | Dr. Bill Campbell

Optimal Protein Podcast with Vanessa Spina

Vanessa Spina

Health & Fitness, Nutrition, Fitness

4.6 • 795 Ratings

🗓️ 18 May 2026

⏱️ 83 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

In this episode, Vanessa Spina is joined again by leading body composition scientist Dr. Bill Campbell for a deep dive into menopause, weight loss resistance, rapid fat loss, protein, muscle preservation, and the newest research coming out of his lab.

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They unpack one of the biggest debates in women's health right now: is menopause-related weight loss resistance real, or are women simply underreporting calories? Dr. Campbell explains why the answer may be more nuanced than social media suggests, and why he is now dedicating much of his research career to studying resistance-trained peri- and postmenopausal women.

Vanessa and Dr. Campbell discuss:

New research on menopause and "weight loss resistance"
Why longitudinal menopause studies matter
Rapid fat loss protocols without lean mass loss
Protein-sparing modified fasting approaches
Sleep deprivation and fat loss resistance
GLP-1 medications, lean mass loss, and weight regain
Why exercise is critical for maintaining weight loss
Protein timing and body recomposition
Reverse dieting and post-diet strategies
Overfeeding carbs vs. fats
Why high protein remains essential for body composition

This episode is packed with practical insights and cutting-edge science for anyone interested in fat loss, muscle preservation, menopause, and metabolic health.

Resources:

Dr. Bill Campbell's Body by Science Research Review: billcampbellphd.com
Follow Vanessa: ketogenicgirl.com

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Follow @optimalproteinpodcast on Instagram to see visuals and posts mentioned on this podcast.

Link to join the Facebook group for the podcast

The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.

Transcript

Click on a timestamp to play from that location

0:00.0	Welcome to the optimal protein podcast. I'm Vanessa Spina.
0:04.5	Hello, my friends. Welcome back to the optimal protein podcast. I'm your host Vanessa.
0:09.9	And today I am absolutely thrilled to welcome back one of my favorite guests, Dr. Bill Campbell.
0:17.8	Dr. Campbell is truly one of the leading body composition scientists in the world,
0:23.2	and what makes his work so incredibly valuable for this podcast is that he doesn't just
0:29.8	study fat loss and muscle building in theory. He studies the exact questions that so many
0:36.4	women are asking right now. Why does fat loss feel
0:40.0	harder in midlife? Does menopause change body composition? Is weight loss resistance real? Can
0:48.4	women preserve muscle during more aggressive fat loss? How much protein do we really need for body composition? And what actually
0:56.6	helps us to maintain our fat loss after a diet? In this conversation, we get into Dr. Campbell's
1:03.8	recent research. He actually did a rapid fat loss protocol and found remarkably surprising results, which we get into in-depth, as well as
1:14.1	his recent research on resistance trained Perry and postmenopausal women, weight loss resistance,
1:20.1	hormone therapy, protein sparing approaches, GLP1 medications, protein timing, reverse dieting,
1:26.9	and why protein continues to be one of the
1:30.1	most powerful tools for improving body composition. Dr. Campbell truly is a champion for women's
1:36.8	health, and I am so thankful for the work that he is doing to bring real science and validation
1:43.2	to women who are navigating fat loss, muscle
1:46.3	preservation, and the menopause transition. This is such an important and timely conversation.
1:52.7	I cannot wait for you all to hear it. Now before we get into today's episode, I have something
1:58.4	really exciting to share with you all. I am officially
2:01.9	kicking off my biggest sale of the year, the Memorial Day sale, and I am kicking it off
2:08.1	early this year. So as of today, you can save big on the entire Tone Lux collection of
	...

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