Neurophysiologist Shares Top 3 Drivers of Alzheimer’s Disease, How To Reduce Your Risk of Cognitive Decline At Any Age, and How to Build a Super-Brain with Louisa Nicola (Rebroadcast)

Dhru Purohit Show

Dhru Purohit

Medicine, Health & Fitness, Alternative Health

4.7 • 3.4K Ratings

🗓️ 28 May 2025

⏱️ 105 minutes

🔗️ Recording | iTunes | RSS

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Summary

This episode is brought to you by Momentous, Levels, and Branch Basics. Alzheimer’s doesn’t begin at diagnosis—it starts decades earlier. That means the choices we make right now can have a major impact on our brain health down the line. But with so much conflicting health advice out there, how do you know what really moves the needle? Today’s guest cuts through the noise and shares the most effective, science-backed strategies to protect your brain, no matter your age. Today on The Dhru Purohit Show, we’re revisiting one of our favorite episodes with neurophysiologist Louisa Nicola. Louisa shares the top three lifestyle factors that can influence our risk for Alzheimer’s disease. She helps us sort through the most current research and uncovers the biggest myths. She also shares the top two supplements that are critical for protecting brain health and the optimal prescription for exercise and resistance training. Looking to protect your brain health? Louisa shows us how. Louisa Nicola, an Australian-born neurophysiologist and sports scientist, has made significant strides in the field of brain performance and human potential. In 2016, she founded Neuro Athletics, a consulting firm dedicated to optimizing brain health and performance for athletes, executives, and high performers. Louisa's innovative methods improve reaction times, decision-making, and mental acuity. Her vision is to expand Neuro Athletics' reach, empowering more individuals to achieve their full potential through enhanced brain function and mental resilience. In this episode, Dhru and Louisa dive into: The alarming increase in Alzheimer's disease despite genetics (00:33) Why sleep is a critical factor in preventing disease (2:43) The impact of a sedentary lifestyle on increasing your risk for Alzheimer’s disease and tips for beginners (17:47) Physiology as we age (34:35) Fundamental pillars of nutrition and the power of Omega-3 fatty acids (42:20) Creatine for neuroprotection, energy, and reversing osteoporosis (54:02) The biggest myth about Alzheimer’s disease (01:02:51) What motivated Louisa to study Alzheimer’s disease (01:05:44) Actionable steps you can implement to reduce your risk (01:08:50) Implementing sauna into your routine to induce good stress (01:12:13) Brain optimization beyond the fundamentals (01:15:12) Social connections that power health (01:23:18) Bigger muscles-better brain health (01:31:20) Also mentioned in this episode: Omega Quant Test Neuroathletics Instagram Sleep Regularity as a Predictor of All-Cause Mortality Study For more on Louisa, follow her on Instagram, Twitter, and YouTube, or visit her Website. This episode is brought to you by Momentous, Levels, and Branch Basics. Optimize your energy and mental clarity with the Momentous Three: Protein, Omega-3s, and Creatine made by and used by the best. Head to livemomentous.com and use code DHRU for 35% off your first subscription. Right now, Levels is offering my listeners an additional 2 FREE months of the Levels annual Membership when you use my link: levels.link/DHRU. Make moves on your metabolic health with Levels today. Right now, Branch Basics is offering 15% off the Premium Starter Kit; just go to branchbasics.com and use coupon code DHRU. Make 2025 your cleanest, healthiest year yet with Branch Basics! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	Louisa, welcome to the podcast.
0:02.3	You know, I want to start off with something pretty mind-blowing that I learned from you.
0:06.0	So globally, we have about 50, 55 million people diagnosed with Alzheimer's disease.
0:11.4	But the crazy part is that that's set to triple by, I think, 2050 is what I learned from you.
0:18.4	But even crazier than that is that only three to five percent of all diagnoses are driven
0:25.9	by our genetics.
0:27.8	So that begs the question for myself and our audience, what the heck is happening for the other
0:34.6	95 to 97 percent of people who, unfortunately unfortunately are ending up with this super scary disease.
0:42.9	It is super scary. So you're right. Fifty five million people worldwide have Alzheimer's disease.
0:47.3	That number will triple by the year 2050. And it seems to be a cascade of different factors that affect it.
0:55.8	It's my sole understanding that it comes down to three factors.
0:59.9	The first one being inactivity, so lack of exercise, lack of adequate sleep, and then
1:08.4	lack of proper nutrition.
1:10.3	Let's unpack those. Let's start off with the first one, which I actually want to lack of proper nutrition. Let's unpack those.
1:11.6	Let's start off with the first one, which I actually want to kind of go out of order.
1:15.6	Yeah.
1:16.6	So let's start off with the first one and talk about sleep.
1:19.6	Everybody sleeps, or you would hope so, but what is going on in our modern day society
1:25.6	that we're not sleeping good enough that's impacting our brain?
1:30.9	Well, we have to understand, first of all, the pathophysiology of Alzheimer's disease.
1:36.0	So we know in these neurodegenerative diseases, okay?
1:40.8	Neurodegenerative.
	...

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