Nature Podcast: 29 October 2015
Nature Podcast
podcast@nature.com
4.5 • 893 Ratings
🗓️ 28 October 2015
⏱️ 26 minutes
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| 0:00.0 | This week, finding a use for carbon dioxide. |
| 0:05.0 | Right now it's considered a waste. We just release it into the atmosphere and do nothing with it. |
| 0:11.0 | And stem cells offer a test bed for therapies aimed at bipolar disorder. |
| 0:16.0 | We would be able to take cells from patients that have had an episode, and we could screen these |
| 0:22.1 | cells to assist the physician in the prescription of drugs they'd be most effective. |
| 0:28.0 | Plus tracking cancers to stop their spread. This is the Nature Podcast for October the 29th, |
| 0:33.3 | 2015. I'm Kerry Smith. And I'm Adam Levy. |
| 0:40.5 | Our cells get rid of waste proteins in little packages called exosomes that float around in our blood before being flushed from the body. |
| 0:49.0 | Cancer cells are no exception. They shed exosomes too. That means they can be detected in the blood |
| 0:55.3 | and potentially used to diagnose cancers early. This might ring a bell because on the show |
| 1:00.7 | back in June we had researcher Raghu Kuluri and he had been working on using exosomes to |
| 1:05.7 | catch cancer. And our interest was to ask the question, since every cell type releases these particles called exosomes, |
| 1:14.7 | is there a way to identify them that are released by the cancer cells? |
| 1:19.7 | And that would then give us an idea of the cancer load that the patient may have |
| 1:25.9 | and what type of things that you can identify in the |
| 1:28.6 | exosome that could potentially be being derived from the cancer cells. |
| 1:33.2 | Raghu Kuluri from the University of Texas back in June. Now, a group of researchers has moved |
| 1:38.7 | the story on. They say that not only can they diagnose cancer, they can predict its next move. |
| 1:45.1 | You see, exosomes have been shown to play an important role in metastasis, |
| 1:49.5 | the process by which a tumor spreads to other organs. |
| 1:52.9 | Exosomes act a bit like scouts seeking out new locations |
| 1:56.2 | and preparing the sites for tumor cells to grow in. |
... |
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