So, guys, Derek, moreplacemoredates.com. Today we're going to be talking about attenuating the

cardiovascular, potential cardiovascular side effects of nandrolone, because we see, you know, all this

rodent data about how terrible it is for the heart. It's like one of the worst anabolic for the heart

according to all the rodent studies. But in real life, practical application does this really play out?

And on top of that, even in the rodent models, what has shown? But in real life, practical application does this really play out?

And on top of that, even in the rodent models, what has shown to attenuate the cardiovascular

deleterious side effects of Nandrolone, this is really interesting and is something that can

be directly applicable in a human context for potentially mitigating a significant amount of its risk profile.

So there's two studies we're going to be looking at here that are very insightful and they

evaluate two different classes of drugs. The first one is a bit of a shorter study. We're going to

get into the more in-depth one using an ARB after. So the first one

is the role of renin angiotensin system in the nandrolone decanoid induced attenuation of the

bezold jarish reflex. So that's a lot of fancy words, but basically what you need to know,

nandrolone is known to cause cardiovascular abnormalities, such as attenuation of the bezzled, jarish reflex, B.JR, cardiac hypertrophy, which is like the mass gain of the heart, like your heart getting bigger.

And the elevation of mean arterial pressure. Furthermore, a relationship between androgens and the renin

angiotensin system has been reported RAS for abbreviation. The purpose of the study was to

evaluate the influence of RAS on the BJR. So just remember when I say RAS, I'm talking about renin angiotensin

angiotensin system, which is exactly what this drug in the study is addressing.

And then the response of this bezel or jarish reflex BJR to that drug essentially cardiac and prostateic hypertrophy.

So like the effect on the heart and the prostate and mean arterial pressure MAP evoked by

Nandrolone dekanoid.

So getting into the study itself basically what they did was like obviously historically

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