Most replayed moment: Reduce anxiety by improving your gut health | Uma Naidoo
ZOE Science & Nutrition
ZOE
4.6 • 5.6K Ratings
🗓️ 24 March 2026
⏱️ 14 minutes
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| 0:00.0 | Hello and welcome to Zoe Recap, where each week we find the best bits from one of our podcast episodes to help you improve your health. |
| 0:09.0 | Today we're looking at a novel way to improve our mental health. |
| 0:13.0 | If I've learned anything from hosting this podcast, it's just how interconnected all the systems in our body are. |
| 0:19.0 | Nothing works in isolation, which means |
| 0:21.9 | we often have to step back and look at the bigger picture if we want to improve a particular |
| 0:25.8 | aspect of our health. With this in mind, let's shift our focus on mental health. Can we |
| 0:31.7 | approach it from a different angle? Harvard nutritional psychiatrist Dr. Uma Naidu is here to explain the science behind the gut brain axis |
| 0:39.6 | and how you can help one to help the other. |
| 0:46.0 | Nutritional psychiatry and certainly when I practice nutritional lifestyle and metabolic |
| 0:50.9 | psychiatry is an evolving size. It's nascent and there's new evolving evidence every single day. |
| 0:57.7 | But what we do know is that the trillions of microbes that live in our microbiome, in our gut, |
| 1:03.8 | as they're helping with the process of digesting our food, |
| 1:06.9 | their breakdown products are also in the same environment as 90 to 95% of serotonin |
| 1:14.0 | receptors. Now, serotonin is often called the happiness hormone. There are serotonin the brain |
| 1:20.5 | and other parts, but there's 90 to 95% of the receptors in serotonin production happens in the gut. |
| 1:27.8 | So the linkage that I make that's been backed up by science is that as our food is being |
| 1:32.7 | digested, it's also in the same environment as where these neurotransmitters are being produced, |
| 1:38.4 | where the receptors are located. |
| 1:40.8 | So we are therefore really understanding more and more that mental health is not this impact of just the brain. |
| 1:48.8 | It's the brain in connection with the gut and other parts of the body. |
| 1:52.6 | And can you explain a little bit more like what is a serotonin receptor? |
| 1:57.8 | And if it's in my gut, how's that linked to my brain? And how does that then make me |
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