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ZOE Science & Nutrition

Most replayed moment: Do You Have High-Functioning Depression? | Dr Judith Joseph & Professor Sarah Berry

ZOE Science & Nutrition

ZOE

Nutrition, Education, Science, Health & Fitness

4.65.6K Ratings

🗓️ 5 May 2026

⏱️ 15 minutes

🧾️ Download transcript

Summary

Today, we’re shining a light on a lesser-known form of depression. When we imagine depression, we often think of someone unable to get out of bed, someone who struggles to complete daily tasks. However, many people with depression are the exact opposite. They meet deadlines, achieve goals and appear successful. Yet, on the inside, they feel disconnected and distant from joy.  This quieter, harder-to-spot condition is known as high-functioning depression. I’m joined by psychiatrist Dr. Judith Joseph and Professor Sarah Berry to unpack what high-functioning depression looks like, why it’s so frequently missed, and how we should approach it. Sarah starts by asking for clarity on a word that is closely connected to this condition. 🌱 Try our science-backed and tasty wholefood supplement Daily 30+ Get our brand-new app and Gut Health Test designed by world-leading gut health and nutrition scientists to build healthy eating habits 👉 Join ZOE Follow ZOE on Instagram. 📚Books by our ZOE Scientists The Food For Life Cookbook Every Body Should Know This by Dr Federica Amati Food For Life by Prof. Tim Spector Ferment by Prof. Tim Spector Free resources from ZOE Eating for Better Brain Health: Your brain-gut blueprint How to eat in 2026 - Discover ZOE’s 8 nutrition principles for long-term health Live Healthier: Top 10 Tips From ZOE Science & Nutrition Gut Guide - For a Healthier Microbiome in Weeks  Better Breakfast Guide

Transcript

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0:00.0

Hello and welcome to Zoe Recap, where each week we find the best bits from one of our podcast episodes to help you improve your health.

0:09.0

When we imagine depression, we often think of someone unable to get out of bed, someone who struggles to complete daily tasks.

0:17.0

However, many people with depression are the exact opposite.

0:21.6

They meet deadlines, achieve goals and appear successful.

0:24.6

Yet on the inside, they feel disconnected and distant from joy.

0:28.6

This quieter, harder to spot condition is called high functioning depression.

0:33.6

I'm joined by psychiatrist Dr Judith Joseph and Sarah Berry to unpack what high-functioning

0:40.2

depression looks like, why it's so frequently missed, and how we should approach it. Sarah starts by

0:45.7

asking for clarity on a word that is closely connected to this condition. Anhedonia, I have never

0:53.0

heard of that word. Could you explain what that means?

0:55.7

So it's actually a word that if you ask any nurse, any healthcare professional, they know what it is.

1:01.0

It's such an antiquated old medical word.

1:03.4

Okay. Had you heard of it, Jonathan?

1:05.4

No, no, go on.

1:06.6

I want to know. Have you heard of it?

1:08.2

No.

1:08.6

Most people haven't. That's okay.

1:10.4

It was really coined by a French

1:12.6

psychologist, I think he may have been a psychiatrist in the 1800s. And what he was seeing was this

1:17.9

lack of pleasure and interest in things in people who had substance abuse, and people who had

1:23.4

depression and people who had schizophrenia. And that's where you see a lot of anadonia.

1:27.8

You even see it in people with dementia. So, you know, older people who are going through that

...

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