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The Gist

Mike Pesca on Lifelong: The Bliss Molecule and the Psychology of Weight Loss

The Gist

Peach Fish Productions

Daily News, News

4.53.7K Ratings

🗓️ 7 March 2026

⏱️ 43 minutes

🧾️ Download transcript

Summary

For this Saturday Show, Mike takes the guest seat on Lifelong with Ethan Suplee. Actor Ethan Suplee (Remember the Titans, My Name Is Earl) is well-known for his incredible physical transformation, having lost hundreds of pounds. Together, he and Mike get into a deep, candid discussion about the lifelong psychology of weight management, the economic politics of GLP-1 drugs, and why the extremes of the "Healthy at Every Size" movement veer into anti-science cultism. Plus, Mike reveals his biological "bliss molecule" advantage against anxiety. https://www.americanglutton.net/listen Produced by Corey Wara Video and Social Media by Geoff Craig Do you have questions or comments, or just want to say hello? Email us at ⁠⁠⁠⁠thegist@mikepesca.com For full Pesca content and updates, check out our website at https://www.mikepesca.com/⁠ For ad-free content or to become a Pesca Plus subscriber, check out ⁠⁠⁠⁠https://subscribe.mikepesca.com/ For Mike's daily takes on Substack, subscribe to The Gist List https://mikepesca.substack.com/ Follow us on Social Media:⁠⁠⁠⁠ YouTube https://www.youtube.com/channel/UC4_bh0wHgk2YfpKf4rg40_g⁠⁠⁠⁠ Instagram https://www.instagram.com/pescagist/ X https://x.com/pescami TikTok https://www.tiktok.com/@pescagist To advertise on the show, contact ⁠⁠⁠⁠ad-sales@libsyn.com⁠⁠⁠⁠ or visit ⁠⁠⁠⁠https://advertising.libsyn.com/TheGist

Transcript

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0:00.0

Money shapes everything.

0:02.0

Our relationships, the choices we make, how we see ourselves.

0:06.0

I'm Riemérez, and on this is uncomfortable, we navigate the practical and emotional side of money.

0:11.0

Whether you're doing quiet math about how to support your family, or bracing for a hard financial conversation with a partner,

0:18.0

or staring down a bill you didn't see coming. We share the kind of stories

0:21.7

that help you feel a little less alone in those moments. Be sure to listen to This is Uncomfortable

0:26.9

every Thursday on your favorite podcast app.

0:33.6

Hi, it's Saturday. It's the Saturday show, and this week I'm going to bring you an appearance I had on another show, another, not mostly a podcast. It's a video show on the two-way network. And it is called Lifelong with Ethan Supley. Do you know Ethan Supley? You just might. He was Earl's brother in My Name is Earl. He was in Remember the Titans. Remember, remember the Titans? Remember the

0:55.6

offensive linemen who had to remember a key play in remember. Do you remember him remembering and

1:00.5

remember the Titans? Ethan was in that. And he was, and still is, a very fine actor, but for most

1:06.1

American history acts, he was in, for most of his career, his type, because this was who he was, was a very

1:13.2

overweight guy. And at times he weighed, and I don't know if he was acting at this weight,

1:18.3

but he reached over 500 pounds. So even though he was in demand as either the funny fat guy or

1:25.8

the tough fat guy, the fat guy. Even though he was in demand,

1:30.3

and even though this was part of his career, he knew he had to change something and he did.

1:35.1

And now, if you see Ethan, he goes to the gym a lot and he's really jacked and the materials

1:40.6

for his show and a lot of the other YouTube videos he's on is look at how this actor

1:45.1

went from 500 pounds to you know ripped Adonis so Ethan has this show he talks a lot it's

1:52.5

it's not about you know where to position your legs during a Bulgarian split squat but we do

1:58.0

I do mention the Bulgarian split squat I so do love the Bulgarian split squat.

2:02.1

We talk about mental states. We talk. He knows a lot about nutrition. And he talked about me and my,

2:07.9

I'm going to say similar journey, but I was, you know, basically not. I didn't go through it

...

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